Biomaterials have had an increasingly important role in recent decades, in biomedical
device design and the development of tissue engineering solutions for cell delivery, drug …

The extracellular matrix is perturbed in tumors. The tumor matrix promotes the growth,
survival, and invasion of the cancer and modifies fibroblast and immune cell behavior to …

Integrin receptor activation initiates the formation of integrin adhesion complexes (IACs) at
the cell membrane that transduce adhesion-dependent signals to control a multitude of …

Heparan sulfate proteoglycans are found at the cell surface and in the extracellular matrix,
where they interact with a plethora of ligands. Over the last decade, new insights have …

Syndecans are a small family of four transmembrane proteoglycans in mammals. They have
similar structural organization, consisting of an N‐terminal ectodomain, single …

How various macromolecules are exchanged between cells and how they gain entry into
recipient cells are fundamental questions in cell biology with important implications eg non …

Directional migration is an important component of cell motility. Although the basic
mechanisms of random cell movement are well characterized, no single model explains the …

The extracellular matrix (ECM) microenvironment plays a central role in cell migration by
providing physiochemical information that influences overall cell behavior. Much of this …

A major challenge for successful cultured meat production is the requirement for large
quantities of skeletal muscle satellite cells (MuSCs). Commercial microcarriers (MCs), such …

We search in this paper for context-specific modes of three-dimensional (3D) cell migration
using imaging for phosphatidylinositol (3, 4, 5)-trisphosphate (PIP3) and active Rac1 and …