Radiological images have been assessed qualitatively in most clinical settings by the expert
eyes of radiologists and other clinicians. On the other hand, quantification of radiological …

Chronic obstructive pulmonary disease (COPD) is a multifaceted disease in which the
pulmonary vessels are often affected (1, 2). Mild pulmonary hypertension (PH) is a common …

Background Exacerbations of chronic obstructive pulmonary disease (COPD) are
associated with accelerated loss of lung function and death. Identification of patients at risk …

Pulmonary hypertension remained an unexplained intractable disease with poor prognosis.
In the last 2 decades, however, the diagnosis and treatment methods for this disease …

Pulmonary hypertension (PH) is highly heterogeneous and despite treatment advances it
remains a life-shortening condition. There have been significant advances in imaging …

Rationale: Angiographic investigation suggests that pulmonary vascular remodeling in
smokers is characterized by distal pruning of the blood vessels. Objectives: Using volumetric …

The Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) study,
which began in 2007, is an ongoing multicenter observational cohort study of more than …

Background COPD is associated with significant morbidity primarily driven by acute
exacerbations. Relative pulmonary artery (PA) enlargement, defined as a PA to ascending …

The loss of pulmonary vessels has been shown to be related to the severity of pulmonary
hypertension in patients with chronic obstructive pulmonary disease (COPD). The severity of …

Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare complication of acute
pulmonary embolism. Important advances have enabled better understanding …