Oxidative stress mitigation by antioxidants-an overview on their chemistry and influences on health status

AM Pisoschi, A Pop, F Iordache, L Stanca… - European Journal of …, 2021 - Elsevier
The present review paper focuses on the chemistry of oxidative stress mitigation by
antioxidants. Oxidative stress is understood as a lack of balance between the pro-oxidant …

Superoxide dismutases: Dual roles in controlling ROS damage and regulating ROS signaling

Y Wang, R Branicky, A Noë, S Hekimi - Journal of Cell Biology, 2018 - rupress.org
Superoxide dismutases (SODs) are universal enzymes of organisms that live in the
presence of oxygen. They catalyze the conversion of superoxide into oxygen and hydrogen …

Therapeutic uses of natural astaxanthin: An evidence-based review focused on human clinical trials

A Donoso, J González-Durán, AA Muñoz… - Pharmacological …, 2021 - Elsevier
Astaxanthin is a natural C40 carotenoid with numerous reported biological functions, most of
them associated with its antioxidant and anti-inflammatory activity, standing out from other …

Reticular pseudodrusen: a critical phenotype in age-related macular degeneration

Z Wu, EL Fletcher, H Kumar, U Greferath… - Progress in retinal and …, 2022 - Elsevier
Reticular pseudodrusen (RPD), or subretinal drusenoid deposits (SDD), refer to distinct
lesions that occur in the subretinal space. Over the past three decades, their presence in …

[HTML][HTML] Effects of blue light on the circadian system and eye physiology

G Tosini, I Ferguson, K Tsubota - Molecular vision, 2016 - ncbi.nlm.nih.gov
Light-emitting diodes (LEDs) have been used to provide illumination in industrial and
commercial environments. LEDs are also used in TVs, computers, smart phones, and …

Superoxide dismutases and superoxide reductases

Y Sheng, IA Abreu, DE Cabelli, MJ Maroney… - Chemical …, 2014 - ACS Publications
Superoxide, O2•−, is formed in all living organisms that come in contact with air, and,
depending upon its biological context, it may act as a signaling agent, a toxic species, or a …

Role of reactive oxygen species in the progression of Alzheimer's disease

S Bhatt, L Puli, CR Patil - Drug discovery today, 2021 - Elsevier
Highlights•Oxidative stress is an etiopathogenic event upstream to Aβ-plaques and
neurofibrillary tangles leading to Alzheimer's disease.•Unquenched ROS perturb the …

Soft drusen in age-related macular degeneration: biology and targeting via the oil spill strategies

CA Curcio - Investigative ophthalmology & visual science, 2018 - iovs.arvojournals.org
AMD is a major cause of legal blindness in older adults approachable through
multidisciplinary research involving human tissues and patients. AMD is a vascular …

Paradoxical roles of antioxidant enzymes: basic mechanisms and health implications

XG Lei, JH Zhu, WH Cheng, Y Bao… - Physiological …, 2016 - journals.physiology.org
Reactive oxygen species (ROS) and reactive nitrogen species (RNS) are generated from
aerobic metabolism, as a result of accidental electron leakage as well as regulated …

Potential role of oxidative stress in ocular surface inflammation and dry eye disease

M Dogru, T Kojima, C Simsek… - … ophthalmology & visual …, 2018 - iovs.arvojournals.org
Reactive oxygen species (ROS) are produced as a by-product during the mitochondrial
respiration of the oxygen and potentially able to damage the tissues. Oxidative stress occurs …