Marek's disease virus: from miasma to model
Marek's disease virus (MDV) is an oncogenic herpesvirus that causes various clinical
syndromes in its natural host, the chicken. MDV has long been of interest as a model …
syndromes in its natural host, the chicken. MDV has long been of interest as a model …
Marek's disease vaccines: a solution for today but a worry for tomorrow?
IM Gimeno - Vaccine, 2008 - Elsevier
Marek's disease (MD) is a lymphoproliferative disease of chickens that, in the absence of
control measures, is capable of causing devastating losses in commercial poultry flocks. MD …
control measures, is capable of causing devastating losses in commercial poultry flocks. MD …
The complementary strand of the human T-cell leukemia virus type 1 RNA genome encodes a bZIP transcription factor that down-regulates viral transcription
G Gaudray, F Gachon, J Basbous… - Journal of …, 2002 - Am Soc Microbiol
The RNA genome of the human T-cell leukemia virus type 1 (HTLV-1) codes for proteins
involved in infectivity, replication, and transformation. We report in this study the …
involved in infectivity, replication, and transformation. We report in this study the …
Pathogenesis of Marek's disease virus infection
BW Calnek - Marek's disease, 2001 - Springer
The term pathogenesis is most simply defined as the development of disease. Many
uncomplicated infectious diseases proceed in a direct fashion from infection to a specific …
uncomplicated infectious diseases proceed in a direct fashion from infection to a specific …
The genome of a very virulent Marek's disease virus
Here we present the first complete genomic sequence, with analysis, of a very virulent strain
of Marek's disease virus serotype 1 (MDV1), Md5. The genome is 177,874 bp and is …
of Marek's disease virus serotype 1 (MDV1), Md5. The genome is 177,874 bp and is …
Marek's disease virus-encoded Meq gene is involved in transformation of lymphocytes but is dispensable for replication
Marek's disease virus (MDV) causes an acute lymphoproliferative disease in chickens,
resulting in T cell lymphomas in visceral organs and peripheral nerves. Earlier studies have …
resulting in T cell lymphomas in visceral organs and peripheral nerves. Earlier studies have …
Evolution of Marek's disease–a paradigm for incessant race between the pathogen and the host
V Nair - The Veterinary Journal, 2005 - Elsevier
Marek's disease (MD) is a highly contagious lymphoproliferative disease of poultry caused
by the oncogenic herpesvirus designated Marek's disease virus (MDV). MD has a worldwide …
by the oncogenic herpesvirus designated Marek's disease virus (MDV). MD has a worldwide …
Differential cytokine responses following Marek's disease virus infection of chickens differing in resistance to Marek's disease
P Kaiser, G Underwood, F Davison - Journal of virology, 2003 - Am Soc Microbiol
The production of cytokine mRNAs, in addition to viral DNA, was quantified by real-time
quantitative reverse transcription-PCR (RT-PCR)(cytokines) or PCR (virus) in splenocytes …
quantitative reverse transcription-PCR (RT-PCR)(cytokines) or PCR (virus) in splenocytes …
Marek's Disease Virus Encodes MicroRNAs That Map to meq and the Latency-Associated Transcript
J Burnside, E Bernberg, A Anderson, C Lu… - Journal of …, 2006 - Am Soc Microbiol
MicroRNAs (miRNAs) are a class of small (∼ 22-nucleotide) regulatory molecules that block
translation or induce degradation of target mRNAs. These have been identified in a wide …
translation or induce degradation of target mRNAs. These have been identified in a wide …
The complete unique long sequence and the overall genomic organization of the GA strain of Marek's disease virus
We have determined the DNA sequence of the unique long (UL) region and the repeat long
(RL) region in the genome of serotype 1 GA strain of Marek's disease virus (MDV), a …
(RL) region in the genome of serotype 1 GA strain of Marek's disease virus (MDV), a …