[HTML][HTML] Copper homeostasis and copper-induced cell death in the pathogenesis of cardiovascular disease and therapeutic strategies

X Chen, Q Cai, R Liang, D Zhang, X Liu, M Zhang… - Cell death & …, 2023 - nature.com
Copper is a vital mineral, and an optimal amount of copper is required to support normal
physiologic processes in various systems, including the cardiovascular system. Over the …

Copper homeostasis and cuproptosis in cardiovascular disease therapeutics

L Yang, P Yang, GYH Lip, J Ren - Trends in pharmacological sciences, 2023 - cell.com
Copper (Cu) homeostasis is gaining increasing attention in human health as both Cu
overload and deficiency evokes pathological changes including cardiovascular diseases …

Betanin as a multipath oxidative stress and inflammation modulator: A beetroot pigment with protective effects on cardiovascular disease pathogenesis

DVT Silva, DS Baiao, VF Ferreira… - Critical Reviews in …, 2021 - Taylor & Francis
Oxidative stress is a common physiopathological condition enrolled in risk factors for
cardiovascular diseases. Individuals in such a redox imbalance status present endothelial …

[HTML][HTML] Health-promoting potential of betalains in vivo and their relevance as functional ingredients: A review

P Martínez-Rodríguez, MA Guerrero-Rubio… - Trends in Food Science …, 2022 - Elsevier
Background Betalains are phytochemicals of relevance to the food industry not only for their
natural presence in foods and beverages but also due to their utility as food colorants …

[HTML][HTML] The neuroprotective effect of betanin in trimethyltin-induced neurodegeneration in mice

W Thong-Asa, S Prasartsri, N Klomkleaw… - Metabolic Brain …, 2020 - Springer
Betanin, a natural food colorant with powerful antioxidative properties, has not been studied
in terms of neurodegenerative disease intervention. Therefore, the present study aimed to …

Encapsulation of Selenium nanoparticles and Metformin in macrophage-derived cell membranes for the treatment of spinal cord Injury

X Liu, J Sun, J Du, J An, Y Li, Y Hu… - ACS Biomaterials …, 2023 - ACS Publications
Spinal cord injury is an impact-induced disabling condition. A series of pathological changes
after spinal cord injury (SCI) are usually associated with oxidative stress, inflammation, and …

[HTML][HTML] Benefits of betanin in rotenone-induced Parkinson mice

W Thong-Asa, S Jedsadavitayakol… - Metabolic brain …, 2021 - Springer
The present study aimed to investigate betanin's neuroprotective effect in mice with rotenone-
induced Parkinson-like motor dysfunction and neurodegeneration. Forty male ICR mice …

Supplementation with vitamin E, Zinc, Selenium, and copper re-establishes T-cell function and improves motor recovery in a rat model of spinal cord injury

E Garcia, F Hernández-Ayvar… - Cell …, 2022 - journals.sagepub.com
Spinal cord injury (SCI) causes a dysfunction of sympathetic nervous system innervation that
affects the immune system, leading to immunosuppression syndrome (ISS) and contributing …

[HTML][HTML] Identification of cuproptosis-related biomarkers and analysis of immune infiltration in allograft lung ischemia-reperfusion injury

J Qin, X Xiao, S Li, N Wen, K Qin, H Li, J Wu… - Frontiers in Molecular …, 2023 - frontiersin.org
Background: Allograft lung ischemia-reperfusion injury (ALIRI) is a major cause of early
primary graft dysfunction and poor long-term survival after lung transplantation (LTx); …

Inhibition of scopolamine‐induced memory and mitochondrial impairment by betanin

A Salimi, M Sabur, M Dadkhah… - Journal of Biochemical …, 2022 - Wiley Online Library
Mitochondrial dysfunction and oxidative stress are identified to contribute to the mechanisms
responsible for the pathogenesis of Alzheimer's disease (AD). Scopolamine (SCO) as a …