Poly (ADP-ribose): a dynamic trigger for biomolecular condensate formation
AKL Leung - Trends in cell biology, 2020 - cell.com
Poly (ADP-ribose)(PAR) is a nucleic acid-like protein modification that can seed the
formation of microscopically visible cellular compartments that lack enveloping membranes …
formation of microscopically visible cellular compartments that lack enveloping membranes …
[HTML][HTML] The viral macrodomain counters host antiviral ADP-ribosylation
YMO Alhammad, AR Fehr - Viruses, 2020 - mdpi.com
Macrodomains, enzymes that remove ADP-ribose from proteins, are encoded by several
families of RNA viruses and have recently been shown to counter innate immune responses …
families of RNA viruses and have recently been shown to counter innate immune responses …
[HTML][HTML] The RNA helicase DDX39A binds a conserved structure in Chikungunya virus RNA to control infection
Alphaviruses are a large group of re-emerging arthropod-borne RNA viruses. The compact
viral RNA genomes harbor diverse structures that facilitate replication. These structures can …
viral RNA genomes harbor diverse structures that facilitate replication. These structures can …
ADP-ribose and analogues bound to the deMARylating macrodomain from the bat coronavirus HKU4
RG Hammond, N Schormann… - Proceedings of the …, 2021 - National Acad Sciences
Macrodomains are proteins that recognize and hydrolyze ADP ribose (ADPR) modifications
of intracellular proteins. Macrodomains are implicated in viral genome replication and …
of intracellular proteins. Macrodomains are implicated in viral genome replication and …
In silico studies of fisetin and silymarin as novel chikungunya virus nonstructural proteins inhibitors
Aim: Chikungunya virus (CHIKV) infection is often characterized by fever, rash and
arthralgia. Until now, there is no vaccine or antiviral drug available for this disease. Two …
arthralgia. Until now, there is no vaccine or antiviral drug available for this disease. Two …