Systematic review and individual-patient-data meta-analysis of non-invasive fibrosis markers for chronic hepatitis B in Africa

A Johannessen, AJ Stockdale, MYR Henrion… - Nature …, 2023 - nature.com
Abstract In sub-Saharan Africa, simple biomarkers of liver fibrosis are needed to scale-up
hepatitis B treatment. We conducted an individual participant data meta-analysis of 3,548 …

Hepatocellular carcinoma in sub-Saharan Africa

VVP Kedar Mukthinuthalapati, V Sewram… - JCO global …, 2021 - ascopubs.org
More than 80% of global hepatocellular carcinoma (HCC) patients are estimated to occur in
sub-Saharan Africa (SSA) and Eastern Asia. The most common risk factor of HCC in SSA is …

[HTML][HTML] Chronic hepatitis B infection with low level viremia correlates with the progression of the liver disease

Q Zhang, H Peng, X Liu, H Wang, J Du… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
Methods A retrospective cohort of 674 patients with chronic hepatitis B virus (HBV) infection
who received antiviral treatment for more than 12 months was analyzed for the development …

Extending treatment eligibility for chronic hepatitis B virus infection

AL McNaughton, M Lemoine, C van Rensburg… - Nature Reviews …, 2021 - nature.com
Progress towards hepatitis B virus (HBV) elimination targets remains slow, despite efforts to
support enhanced prevention, diagnosis and treatment. On the basis of insights from …

A new approach to prevent, diagnose, and treat hepatitis B in Africa

CW Spearman, MI Andersson, B Bright… - BMC Global and Public …, 2023 - Springer
There are 82 million people living with hepatitis B (PLWHB) in the World Health
Organization Africa region, where it is the main cause of liver disease. Effective vaccines …

The WHO guidelines for chronic hepatitis B fail to detect half of the patients in need of treatment in Ethiopia

H Aberra, H Desalegn, N Berhe, B Mekasha… - Journal of …, 2019 - Elsevier
Background & Aims In 2015, the World Health Organization (WHO) issued guidelines for the
management of chronic hepatitis B (CHB) in low-and middle-income countries, but little is …

[HTML][HTML] Health inequalities in the management of chronic hepatitis B virus infection in patients from sub-Saharan Africa in high-income countries

T Mitchell, JS Nayagam, G Dusheiko, K Agarwal - JHEP Reports, 2023 - Elsevier
Chronic hepatitis B virus disproportionately affects migrant communities in high-income
countries, reflecting increased migration from sub-Saharan Africa. Chronic hepatitis B virus …

Challenges of hepatitis B treatment in rural Sub‐Saharan Africa: Treatment initiation and outcomes from a public hospital‐based clinic in Kono, Sierra Leone

ET Nyama, LT Allan‐Blitz, R Bitwayiki… - Journal of Viral …, 2023 - Wiley Online Library
Despite a high prevalence, there are few successful models for de‐centralizing diagnosis
and treatment of chronic hepatitis B virus (HBV) infection among rural communities in Sub …

Chronic hepatitis B virus infection in Eastern Ethiopia: Clinical characteristics and determinants of cirrhosis

NY Ismael, SA Usmael, NB Belay… - World Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
BACKGROUND Chronic hepatitis B (CHB) virus infection is a major cause of liver-
associated morbidity and mortality, particularly in low-income countries. A better …

Risks and benefits of oral HIV pre-exposure prophylaxis for people with chronic hepatitis B

AM Mohareb, J Larmarange, AY Kim, PA Coffie… - The Lancet …, 2022 - thelancet.com
Individuals with chronic hepatitis B virus (HBV) infection who are at substantial risk of HIV
acquisition benefit from pre-exposure prophylaxis (PrEP) with tenofovir-based antiviral …