[HTML][HTML] SARS-CoV-2: evolution and emergence of new viral variants

VR Flores-Vega, JV Monroy-Molina… - Viruses, 2022 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent
responsible for the coronavirus disease 2019 (COVID-19). The high rate of mutation of this …

COVID-19 Delta variants—Current status and implications as of August 2021

F Yu, LT Lau, M Fok, JYN Lau… - Precision Clinical …, 2021 - academic.oup.com
Abstract The SARS-CoV-2 Delta variant has evolved as the dominant strain of the current
pandemic. Studies have shown that this variant has increased infectivity/viral load, and …

[HTML][HTML] Comparative analysis of five multiplex RT-PCR assays in the screening of SARS-CoV-2 variants

V De Pace, B Bruzzone, A Orsi, V Ricucci, A Domnich… - Microorganisms, 2022 - mdpi.com
The rapid and presumptive detection of SARS-CoV-2 variants may be performed using
multiplex RT-PCR assays. The aim of this study was to evaluate the diagnostic performance …

[HTML][HTML] Identifying markers of emerging SARS-CoV-2 variants in patients with secondary immunodeficiency

NM Markarian, G Galli, D Patel, M Hemmings… - Frontiers in …, 2022 - frontiersin.org
Since the end of 2019, the world has been challenged by the coronavirus disease 2019
(COVID-19) pandemic. With COVID-19 cases rising globally, severe acute respiratory …

[HTML][HTML] Kappa-RBD produced by glycoengineered Pichia pastoris elicited high neutralizing antibody titers against pseudoviruses of SARS-CoV-2 variants

T Mi, T Wang, H Xu, P Sun, X Hou, X Zhang, Q Ke, J Liu… - Virology, 2022 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) kappa (B. 1.617. 1)
variant represented the main variant of concern (VOC) for the epidemic in India in May 2021 …

[HTML][HTML] COVID-19 Variants and Vaccine Development

Z Zhao, S Bashiri, ZM Ziora, I Toth, M Skwarczynski - Viruses, 2024 - mdpi.com
Coronavirus disease 2019 (COVID-19), the global pandemic caused by severe acute
respiratory syndrome 2 virus (SARS-CoV-2) infection, has caused millions of infections and …

[HTML][HTML] Development and Evaluation of Vaccination Strategies for Addressing the Continuous Evolution SARS-CoV-2 Based on Recombinant Trimeric Protein …

P Du, N Li, S Tang, Z Zhou, Z Liu, T Wang, J Li, S Zeng… - Heliyon, 2024 - cell.com
Given the significant decline in vaccine efficacy against Omicron, the development of novel
vaccines with specific or broad-spectrum effectiveness is paramount. In this study, we …

[HTML][HTML] A vaccine with multiple receptor-binding domain subunit mutations induces broad-spectrum immune response against SARS-CoV-2 variants of concern

XC Hou, HF Xu, Y Liu, P Sun, LW Ding, JJ Yue… - Vaccines, 2022 - mdpi.com
With the emergence of more variants of severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) and the immune evasion of these variants from existing vaccines, the …

[HTML][HTML] Rapid and qualitative identification of SARS-CoV-2 mutations associated with variants of concern using a multiplex RT-PCR assay coupled with melting …

G Sberna, L Fabeni, G Berno, F Carletti… - International Journal of …, 2022 - Elsevier
Objectives Considering the spread of new genetic variants and their impact on public health,
it is important to have assays that are able to rapidly detect SARS-CoV-2 variants. Methods …

[PDF][PDF] Comparative Analysis of Five Multiplex RT-PCR Assays in the Screening of SARS-CoV-2 Variants. Microorganisms 2022, 10, 306

V De Pace, B Bruzzone, A Orsi, V Ricucci, A Domnich… - 2022 - academia.edu
The rapid and presumptive detection of SARS-CoV-2 variants may be performed using
multiplex RT-PCR assays. The aim of this study was to evaluate the diagnostic performance …