Great strides have been made in recent years towards understanding the roles of natural
killer (NK) cells in immunity to tumours and viruses. NK cells are cytotoxic innate lymphoid …

Understanding how signals are integrated to control natural killer (NK) cell responsiveness
in the absence of antigen-specific receptors has been a challenge, but recent work has …

The Fc receptor CD16 is present on essentially all CD56dim peripheral blood natural killer
(NK) cells. Upon recognition of antibody-coated cells it delivers a potent signal to NK cells …

Natural killer (NK) cells survey host tissues for signs of infection, transformation or stress
and, true to their name, kill target cells that have become useless or are detrimental to the …

Our understanding of development and function of natural killer (NK) cells has progressed
significantly in recent years. However, exactly how uterine NK (uNK) cells develop and …

The functional capacities of natural killer (NK) cells differ within and between individuals,
reflecting considerable genetic variation.'Licensing/arming','disarming', and 'tuning'are …

Natural killer (NK) cells possess potent perforin‐and interferon‐γ‐dependent effector
functions that are tightly regulated. Inhibitory receptors for major histocompatibility complex …

Natural killer (NK) cells, similar to other lymphocytes, acquire tolerance to self. This means
that NK cells have the potential to attack normal self cells but that there are mechanisms to …

One of the hallmarks of the vertebrate adaptive immune system is the prolific expansion of
individual cell clones that encounter their cognate antigen. More recently, however, there is …

Receptors carrying immunoreceptor tyrosine‐based inhibition motifs (ITIMs) in their
cytoplasmic tail control a vast array of cellular responses, ranging from autoimmunity …