Hydrogels as drug delivery systems: A review of current characterization and evaluation techniques
Owing to their tunable properties, controllable degradation, and ability to protect labile
drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a …
drugs, hydrogels are increasingly investigated as local drug delivery systems. However, a …
Stimuli‐responsive liposomes for drug delivery
Y Lee, DH Thompson - Wiley Interdisciplinary Reviews …, 2017 - Wiley Online Library
The ultimate goal of drug delivery is to increase the bioavailability and reduce the toxic side
effects of the active pharmaceutical ingredient (API) by releasing them at a specific site of …
effects of the active pharmaceutical ingredient (API) by releasing them at a specific site of …
Nanoparticle delivery improves the pharmacokinetic properties of cyclic dinucleotide STING agonists to open a therapeutic window for intravenous administration
The stimulator of interferon genes (STING) pathway plays an important role in the immune
surveillance of cancer and, accordingly, agonists of STING signaling have recently emerged …
surveillance of cancer and, accordingly, agonists of STING signaling have recently emerged …
Basic principles of drug delivery systems–the case of paclitaxel
S Ezrahi, A Aserin, N Garti - Advances in colloid and interface science, 2019 - Elsevier
Cancer is the second cause of death worldwide, exceeded only by cardiovascular diseases.
The prevalent treatment currently used against metastatic cancer is chemotherapy. Among …
The prevalent treatment currently used against metastatic cancer is chemotherapy. Among …
Targeted delivery system of nanobiomaterials in anticancer therapy: from cells to clinics
SE Jin, HE Jin, SS Hong - BioMed research international, 2014 - Wiley Online Library
Targeted delivery systems of nanobiomaterials are necessary to be developed for the
diagnosis and treatment of cancer. Nanobiomaterials can be engineered to recognize …
diagnosis and treatment of cancer. Nanobiomaterials can be engineered to recognize …
Lysine-embedded cellulose-based nanosystem for efficient dual-delivery of chemotherapeutics in combination cancer therapy
Combination therapy by two or multiple drugs with different mechanisms of action is a
promising strategy in cancer treatment. In this regard, a wide range of chemotherapeutics …
promising strategy in cancer treatment. In this regard, a wide range of chemotherapeutics …
A TPGS-incorporating nanoemulsion of paclitaxel circumvents drug resistance in breast cancer
H Bu, X He, Z Zhang, Q Yin, H Yu, Y Li - International journal of …, 2014 - Elsevier
Paclitaxel resistance is usually developed in clinical chemotherapy, which remains a major
obstacle for successful cancer treatment. Herein, we attempted to develop a TPGS …
obstacle for successful cancer treatment. Herein, we attempted to develop a TPGS …
A nano-in-nano polymer–dendrimer nanoparticle-based nanosystem for controlled multidrug delivery
Codelivery of multiple chemotherapeutics with different action mechanisms is a promising
strategy for cancer treatment. In this study, we developed a novel polymer–dendrimer hybrid …
strategy for cancer treatment. In this study, we developed a novel polymer–dendrimer hybrid …
Multifunctional nanosystem for targeted and controlled delivery of multiple chemotherapeutic agents for the treatment of drug-resistant breast cancer
By targeting CD44 receptors, inhibiting multidrug resistance (MDR), controlling drug release,
and synergistically inhibiting tumor growth, a multilayered nanosystem was developed to …
and synergistically inhibiting tumor growth, a multilayered nanosystem was developed to …
Rational design of polymer-lipid nanoparticles for docetaxel delivery
In this work, a stable nanocarrier for the anti-cancer drug docetaxel was rational designed.
The nanocarrier was developed based on the solid lipid nanoparticle preparation process …
The nanocarrier was developed based on the solid lipid nanoparticle preparation process …