New insights into the composition and functions of the acquired enamel pellicle

WL Siqueira, W Custodio… - Journal of dental …, 2012 - journals.sagepub.com
The acquired enamel pellicle (AEP) is a thin acellular film that forms on tooth surfaces upon
exposure to the oral environment. It consists predominantly of salivary proteins, but also …

Saliva: a dynamic proteome

EJ Helmerhorst, FG Oppenheim - Journal of dental research, 2007 - journals.sagepub.com
The proteome of whole saliva, in contrast to that of serum, is highly susceptible to a variety of
physiological and biochemical processes. First, salivary protein secretion is under …

How does it kill?: understanding the candidacidal mechanism of salivary histatin 5

S Puri, M Edgerton - Eukaryotic cell, 2014 - Am Soc Microbiol
Histatins are salivary cationic peptides that provide the first line of defense against oral
candidiasis caused by Candida albicans. This minireview presents a critical evaluation of …

Salivary proteome and its genetic polymorphisms

FG Oppenheim, E Salih, WL Siqueira… - Annals of the New …, 2007 - Wiley Online Library
Salivary diagnostics for oral as well as systemic diseases is dependent on the identification
of biomolecules reflecting a characteristic change in presence, absence, composition, or …

Identification of Protein Components in in vivo Human Acquired Enamel Pellicle Using LC−ESI−MS/MS

WL Siqueira, W Zhang, EJ Helmerhorst… - Journal of proteome …, 2007 - ACS Publications
The acquired enamel pellicle is a thin protein film forming upon exposure of tooth enamel
surfaces to saliva. The structural analysis of this integument relies on efficient pellicle …

Salivary peptidomics

F Amado, MJC Lobo, P Domingues… - Expert review of …, 2010 - Taylor & Francis
In recent years, there has been an increased interest in the study of saliva. This bodily fluid
contains a vast number of protein species, the salivary peptidome, of low molecular weight …

A Novel Immune Evasion Strategy of Candida albicans: Proteolytic Cleavage of a Salivary Antimicrobial Peptide

TF Meiller, B Hube, L Schild, ME Shirtliff, MA Scheper… - PloS one, 2009 - journals.plos.org
Oropharyngeal candidiasis is an opportunistic infection considered to be a harbinger of
AIDS. The etiologic agent Candida albicans is a fungal species commonly colonizing human …

Cationic antimicrobial peptides are leading the way to combat oropathogenic infections

B Lin, R Li, TNG Handley, JD Wade, W Li… - ACS Infectious …, 2021 - ACS Publications
Oral dental infections are one of the most common diseases affecting humans, with caries
and periodontal disease having the highest incidence. Caries and periodontal disease arise …

Novel impacts of saliva with regard to oral health

H Uchida, CE Ovitt - The journal of prosthetic dentistry, 2022 - Elsevier
The maintenance of balanced oral homeostasis depends on saliva. A readily available and
molecularly rich source of biological fluid, saliva fulfills many functions in the oral cavity …

Proteomic Evaluation of Acquired Enamel Pellicle during In Vivo Formation

YH Lee, JN Zimmerman, W Custodio, Y Xiao, T Basiri… - Plos one, 2013 - journals.plos.org
Acquired enamel pellicle (AEP) is a protein film that forms on the enamel surface of teeth by
selective adsorption of proteins and peptides present in the mouth. This protein film forms …