The immunology of long COVID

DM Altmann, EM Whettlock, S Liu… - Nature Reviews …, 2023 - nature.com
Long COVID is the patient-coined term for the disease entity whereby persistent symptoms
ensue in a significant proportion of those who have had COVID-19, whether asymptomatic …

Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Circulating anti-nuclear autoantibodies in COVID-19 survivors predict long COVID symptoms

K Son, R Jamil, A Chowdhury… - European …, 2023 - Eur Respiratory Soc
Background Autoimmunity has been reported in patients with severe coronavirus disease
2019 (COVID-19). We investigated whether anti-nuclear/extractable-nuclear antibodies …

Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also …

A Kruger, M Vlok, S Turner, C Venter… - Cardiovascular …, 2022 - Springer
Background Post-acute sequelae of COVID-19 (PASC), also now known as long COVID,
has become a major global health and economic burden. Previously, we provided evidence …

Multisystem inflammatory syndrome in children and long COVID: the SARS-CoV-2 viral superantigen hypothesis

M Noval Rivas, RA Porritt, MH Cheng, I Bahar… - Frontiers in …, 2022 - frontiersin.org
Multisystem inflammatory syndrome in children (MIS-C) is a febrile pediatric inflammatory
disease that may develop weeks after initial SARS-CoV-2 infection or exposure. MIS-C …

The potential role of ischaemia–reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and …

DB Kell, E Pretorius - Biochemical Journal, 2022 - portlandpress.com
Ischaemia–reperfusion (I–R) injury, initiated via bursts of reactive oxygen species produced
during the reoxygenation phase following hypoxia, is well known in a variety of acute …

Molecular mimicry and autoimmunity in the time of COVID-19

M Rojas, M Herrán, C Ramírez-Santana… - Journal of …, 2023 - Elsevier
Infectious diseases are commonly implicated as potential initiators of autoimmune diseases
(ADs) and represent the most commonly known factor in the development of autoimmunity in …

COVID‐19 and plasma cells: Is there long‐lived protection?

DC Nguyen, PA Lamothe, MC Woodruff… - Immunological …, 2022 - Wiley Online Library
Summary Infection with SARS‐CoV‐2, the etiology of the ongoing COVID‐19 pandemic, has
resulted in over 450 million cases with more than 6 million deaths worldwide, causing global …

Hypercoagulability, endotheliopathy, and inflammation approximating 1 year after recovery: assessing the long‐term outcomes in COVID‐19 patients

BE Fan, SW Wong, CLL Sum, GH Lim… - American journal of …, 2022 - Wiley Online Library
Sustained hypercoagulability and endotheliopathy are present in convalescent COVID‐19
patients for up to 4 months from recovery. The hemostatic, endothelial, and inflammatory …

Is post-COVID syndrome an autoimmune disease?

JM Anaya, M Herran, S Beltran… - Expert Review of Clinical …, 2022 - Taylor & Francis
ABSTRACT Introduction Post-COVID syndrome (PCS) is recognized as a new entity in the
context of SARS-CoV-2 infection. Though its pathogenesis is not completely understood …