Production of bioactive plant secondary metabolites through in vitro technologies—status and outlook

C Wawrosch, SB Zotchev - Applied Microbiology and Biotechnology, 2021 - Springer
Medicinal plants have been used by mankind since ancient times, and many bioactive plant
secondary metabolites are applied nowadays both directly as drugs, and as raw materials …

[PDF][PDF] Medicinal plants and their secondary metabolites—State of the art and trends in breeding, analytics and use in feed supplementation—With special focus on …

B Faehnrich, C Franz, P Nemaz, HP Kaul - J. Appl. Bot. Food Qual, 2021 - researchgate.net
Plants in ecology interact with their biotic and abiotic environment. Means of interactions,
and thereby crucial for the survival of the species, are secondary plant metabolites …

[PDF][PDF] Callus culture for the production of therapeutic compounds

ED Benjamin, GA Ishaku, FA Peingurta… - American Journal of …, 2019 - researchgate.net
Plant-derived compounds retain a special place in the treatment of various diseases across
the world. Their application cuts across every class of disease, where they are found to be …

Enhancing artemisinin content in and delivery from Artemisia annua: a review of alternative, classical, and transgenic approaches

KI Wani, S Choudhary, A Zehra, M Naeem, P Weathers… - Planta, 2021 - Springer
Main conclusion This review analyses the most recent scientific research conducted for the
purpose of enhancing artemisinin production. It may help to devise better artemisinin …

Current state, strategies, and perspectives in enhancing artemisinin production

AM Zakariya, MZ Saiman, HT Simonsen… - Phytochemistry …, 2024 - Springer
The compound artemisinin is attributed to several biological activities including antimalaria
for which it is popularly known. However, its commercial production is hindered by a low …

AaABF3, an Abscisic Acid–Responsive Transcription Factor, Positively Regulates Artemisinin Biosynthesis in Artemisia annua

Y Zhong, L Li, X Hao, X Fu, Y Ma, L Xie… - Frontiers in Plant …, 2018 - frontiersin.org
Artemisinin is well known for its irreplaceable curative effect on the devastating parasitic
disease, Malaria. This sesquiterpenoid is specifically produced in Chinese traditional herbal …

Medicinal plant research at crossroads: biotechnological approaches for conservation, production and stability in tissue cultures and regenerated plants

M Halder, A Majumder, S Ray, S Jha - Medicinal Plants: Domestication …, 2021 - Springer
Medicinal plants are treasures of nature with almost never-ending resource of unlimited,
diverse, complex and valuable natural compounds with a variety of pharmacological …

Current strategies to improve yield of recombinant protein production in rice suspension cells

YH Chi, LF Huang - Processes, 2022 - mdpi.com
A plant cell-based recombinant glucocerebrosidase was approved by the FDA in 2012 for
the treatment of human inherited Gaucher disease, indicating that plant suspension cells …

Efficient in vitro regeneration of Artemisia annua: effect of different combinations of plant growth regulators on various types of explants

R Soni, A Singh, V Gupta - … An International Journal Dealing with all …, 2024 - Taylor & Francis
The global supply chain of artemisinin for treating malaria relies on the natural population of
Artemisia annua. To enhance artemisinin levels in planta, genetic and molecular …

Recent Biotechnological Approaches for the Enhancement of Artemisinin Production from Cell Culture System of Artemisia annua L.: Medicinal Plant with Potent …

G Mahendran, L Rahman - Natural Product Experiments in Drug …, 2022 - Springer
Artemisinin is the most potent antimalarial drug obtained from Artemisia annua. However,
this metabolite found in low amounts in natural sources has led to its production that is …