Lymph nodes (LNs) are strategically positioned at dedicated sites throughout the body to
facilitate rapid and efficient immunity. Central to the structural integrity and framework of LNs …

Ectopic lymphoid-like structures often develop at sites of inflammation where they influence
the course of infection, autoimmune disease, cancer and transplant rejection. These …

Tertiary lymphoid organs (TLOs) are frequently observed in tissues affected by non-
resolving inflammation as a result of infection, autoimmunity, cancer, and allograft rejection …

Tissue-resident memory T cells (TRM cells) are a population of immune cells that reside in
the lymphoid and non-lymphoid organs without recirculation through the blood. These …

Lymphoid neogenesis is traditionally viewed as a pre‐programmed process that promotes
the formation of lymphoid organs during development. Here, the spatial organization of T …

The salivary glands are important effector sites for IgA-mediated humoral immunity to protect
oral surfaces. Within murine submandibular glands (SMG), we identified a memory CD8 T …

Ectopic lymphoid-like structures (ELSs) reminiscent of secondary lymphoid organs often
develop at sites of chronic inflammation where they contribute to immune-mediated …

Tertiary lymphoid organs (TLOs) develop at ectopic sites within chronically inflamed tissues,
such as in autoimmunity and rejecting organ allografts. TLOs differ structurally from …

While saliva regulates the interplay between the microbiota and the oral immune system, the
mechanisms establishing postnatal salivary immunity are ill-defined. Here, we show that …

Ectopic lymphoid structures (ELS) consist of B-cell and T-cell aggregates that are initiated de
novo in inflamed tissues outside of secondary lymphoid organs. When organized within …