Mechanical ventilation has been used to support acutely ill patients for several decades. But
clinicians are aware that, despite the life-saving potential of this assistance, it has several …

Acute respiratory distress syndrome and acute lung injury are well defined and readily
recognised clinical disorders caused by many clinical insults to the lung or because of …

Background The diagnostic criteria for acute lung injury (ALI) and ARDS utilize the Pa o
2/fraction of inspired oxygen (F io 2)[P/F] ratio measured by arterial blood gas analysis to …

Rationale: Reducing tidal volume decreases mortality in acute respiratory distress syndrome
(ARDS). However, the effect of the timing of low tidal volume ventilation is not well …

Objective To evaluate the association of volume limited and pressure limited (lung
protective) mechanical ventilation with two year survival in patients with acute lung injury …

Introduction The aim of this study was to investigate whether in-hospital mortality was
associated with the administered fraction of oxygen in inspired air (FiO 2) and achieved …

Objective: The objective of this study was to determine the epidemiology and outcomes of
intra-abdominal hypertension in a heterogeneous intensive care unit population. Design …

Study objectives: Recent data have suggested that ventilatory strategy could influence
outcomes from acute lung injury (ALI) and ARDS. We tested the hypothesis that …

Objective To determine the incidence and outcome of severe sepsis in the adult Finnish
population and to evaluate how treatment guidelines in severe sepsis are applied in clinical …

Objectives: To describe the effectiveness of a comprehensive, interdisciplinary sepsis
treatment protocol with regard to both implementation and outcomes and to compare the …