Shattering barriers toward clinically meaningful MSC therapies
More than 1050 clinical trials are registered at FDA. gov that explore multipotent
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …
Direct Cell Radiolabeling for in Vivo Cell Tracking with PET and SPECT Imaging
The arrival of cell-based therapies is a revolution in medicine. However, its safe clinical
application in a rational manner depends on reliable, clinically applicable methods for …
application in a rational manner depends on reliable, clinically applicable methods for …
Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies
P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …
approach for the treatment of cardiovascular diseases. Since the first transplantation into …
Pulmonary passage is a major obstacle for intravenous stem cell delivery: the pulmonary first-pass effect
UM Fischer, MT Harting, F Jimenez… - Stem cells and …, 2009 - liebertpub.com
Intravenous (IV) stem cell delivery for regenerative tissue therapy has been increasingly
used in both experimental and clinical trials. However, recent data suggest that the majority …
used in both experimental and clinical trials. However, recent data suggest that the majority …
Clinical imaging in regenerative medicine
In regenerative medicine, clinical imaging is indispensable for characterizing damaged
tissue and for measuring the safety and efficacy of therapy. However, the ability to track the …
tissue and for measuring the safety and efficacy of therapy. However, the ability to track the …
Stem cell imaging: from bench to bedside
Although cellular therapies hold great promise for the treatment of human disease, results
from several initial clinical trials have not shown a level of efficacy required for their use as a …
from several initial clinical trials have not shown a level of efficacy required for their use as a …
Assessment and optimization of cell engraftment after transplantation into the heart
JV Terrovitis, RR Smith, E Marbán - Circulation research, 2010 - Am Heart Assoc
Myocardial regeneration using stem and progenitor cell transplantation in the injured heart
has recently become a major goal in the treatment of cardiac disease. Experimental studies …
has recently become a major goal in the treatment of cardiac disease. Experimental studies …
In vivo tracking of 111In-oxine labeled mesenchymal stem cells following infusion in patients with advanced cirrhosis
A Gholamrezanezhad, S Mirpour, M Bagheri… - Nuclear medicine and …, 2011 - Elsevier
BACKGROUND: Several animal and few human studies suggest the beneficial role of bone
marrow mesenchymal stem cells (MSCs) in liver cirrhosis. However, little is known about the …
marrow mesenchymal stem cells (MSCs) in liver cirrhosis. However, little is known about the …
Recent advances in positron emission particle tracking: a comparative review
CRK Windows-Yule, MT Herald… - Reports on progress …, 2022 - iopscience.iop.org
Positron emission particle tracking (PEPT) is a technique which allows the high-resolution,
three-dimensional imaging of particulate and multiphase systems, including systems which …
three-dimensional imaging of particulate and multiphase systems, including systems which …
The dark side of the force–constraints and complications of cell therapies for stroke
Cell therapies are increasingly recognized as a promising option to augment the limited
therapeutic arsenal available to fight ischemic stroke. During the last two decades …
therapeutic arsenal available to fight ischemic stroke. During the last two decades …