Synergistic effects of multiple rotors and hydrogen-bond interactions lead to sensitive near-infrared viscosity probes for live-cell microscopy
Abstract Changes in cellular viscosity are associated with various physiological processes
and pathological conditions. To study these cellular processes and functions, highly …
and pathological conditions. To study these cellular processes and functions, highly …
The significant role of the microfilament system in tumors
X Jiang, Y Qin, L Kun, Y Zhou - Frontiers in oncology, 2021 - frontiersin.org
Actin is the structural protein of microfilaments, and it usually exists in two forms: monomer
and polymer. Among them, monomer actin is a spherical molecule composed of a …
and polymer. Among them, monomer actin is a spherical molecule composed of a …
Recent advances on the model, measurement technique, and application of single cell mechanics
Since the cell was discovered by humans, it has been an important research subject for
researchers. The mechanical response of cells to external stimuli and the biomechanical …
researchers. The mechanical response of cells to external stimuli and the biomechanical …
[HTML][HTML] Differential regulation of GUV mechanics via actin network architectures
Actin networks polymerize and depolymerize to construct highly organized structures,
thereby endowing the mechanical phenotypes found in a cell. It is generally believed that …
thereby endowing the mechanical phenotypes found in a cell. It is generally believed that …
High shear stress amplitude in combination with prolonged stimulus duration determine induction of osteoclast formation by hematopoietic progenitor cells
C Bratengeier, A Liszka, J Hoffman… - The FASEB …, 2020 - Wiley Online Library
To date, it is unclear how fluid dynamics stimulate mechanosensory cells to induce an
osteoprotective or osteodestructive response. We investigated how murine hematopoietic …
osteoprotective or osteodestructive response. We investigated how murine hematopoietic …
A high-throughput microfabricated platform for rapid quantification of metastatic potential
S Bhattacharya, A Ettela, J Haydak, CM Hobson… - Science …, 2024 - science.org
Assays that measure morphology, proliferation, motility, deformability, and migration are
used to study the invasiveness of cancer cells. However, native invasive potential of cells …
used to study the invasiveness of cancer cells. However, native invasive potential of cells …
Biomechanical heterogeneity of living cells: comparison between atomic force microscopy and finite element simulation
Atomic force microscopy (AFM) indentation is a popular method for characterizing the
micromechanical properties of soft materials such as living cells. However, the mechanical …
micromechanical properties of soft materials such as living cells. However, the mechanical …
Cytoplasmic viscosity is a potential biomarker for metastatic breast cancer cells
M Dessard, JB Manneville, JF Berret - Nanoscale Advances, 2024 - pubs.rsc.org
Cellular microrheology has shown that cancer cells with high metastatic potential are softer
compared to non-tumorigenic normal cells. These findings rely on measuring the apparent …
compared to non-tumorigenic normal cells. These findings rely on measuring the apparent …
Characterization of the viscoelastic properties of ovarian cancer cells membranes by optical tweezers and quantitative phase imaging
T Lu, B Anvari - Frontiers in physics, 2020 - frontiersin.org
Ovarian cancer is the deadliest gynecological cancer in women. It is a highly metastatic
disease with pelvis, regional lymph nodes, and peritoneal cavity as major sites for tumor …
disease with pelvis, regional lymph nodes, and peritoneal cavity as major sites for tumor …
Modulating cancer cell mechanics and actin cytoskeleton structure by chemical and mechanical stimulations
S Azadi, M Tafazzoli‐Shadpour… - … Research Part A, 2019 - Wiley Online Library
To date, a myriad of strategies has been suggested for targeting the chemical signaling of
cancer cells. Also, biomechanical features are gaining much more attention. These features …
cancer cells. Also, biomechanical features are gaining much more attention. These features …