Strong elastic protein nanosheets enable the culture and differentiation of induced pluripotent stem cells on microdroplets
E Mojares, C Nadal, D Hayler, H Kanso… - Advanced …, 2024 - Wiley Online Library
Advances in stem cell technologies, revolutionizing regenerative therapies and advanced in
vitro testing, require novel cell manufacturing pipelines able to cope with scale up and …
vitro testing, require novel cell manufacturing pipelines able to cope with scale up and …
Biofabrication and biomanufacturing in Ireland and the UK
As we navigate the transition from the Fourth to the Fifth Industrial Revolution, the emerging
fields of biomanufacturing and biofabrication are transforming life sciences and healthcare …
fields of biomanufacturing and biofabrication are transforming life sciences and healthcare …
Growth of mesenchymal stem cells at the surface of silicone, mineral and plant-based oils
L Peng, C Nadal, JE Gautrot - Biomedical Materials, 2023 - iopscience.iop.org
Bioemulsions are attractive platforms for the expansion of adherent cells in bioreactors.
Their design relies on the self-assembly of protein nanosheets at liquid–liquid interfaces …
Their design relies on the self-assembly of protein nanosheets at liquid–liquid interfaces …
[HTML][HTML] Programmed Self-Assembly of DNA Nanosheets with Discrete Single-Molecule Thickness and Interfacial Mechanics: Design, Simulation, and …
K Cervantes-Salguero, YA Gutiérrez Fosado… - Molecules, 2023 - mdpi.com
DNA is programmed to hierarchically self-assemble into superstructures spanning from
nanometer to micrometer scales. Here, we demonstrate DNA nanosheets assembled out of …
nanometer to micrometer scales. Here, we demonstrate DNA nanosheets assembled out of …
Regulation of Tendon Stem Cell Behavior by Designed Nanoporous Topography of Microfibers
Y Ye, Y Xu, Y Hou, D Yin, D Su, Z Zhao - Biomacromolecules, 2023 - ACS Publications
Nano scale topography scaffold is more bioactive and biomimetic than smooth fiber
topographies. Tendon stem cells (TSCs) play important roles in the tendinogenesis of …
topographies. Tendon stem cells (TSCs) play important roles in the tendinogenesis of …
[HTML][HTML] Interfacial mechanics of β-casein and albumin mixed protein assemblies at liquid-liquid interfaces
A Chrysanthou, M Bosch-Fortea, C Nadal… - Journal of Colloid and …, 2024 - Elsevier
Protein emulsifiers play an important role in formulation science, from food product
development to emerging applications in biotechnologies. The impact of mixed protein …
development to emerging applications in biotechnologies. The impact of mixed protein …
Matrix Nanoscale Mechanics Regulates Exosome Production by Mesenchymal Stem Cells
A Chrysanthou, JE Gautrot - Biorxiv, 2023 - biorxiv.org
Complex biotherapeutics such exosomes offer attractive opportunities for cell-free treatment
of disease and conditions difficult to address with single, defined compounds. However their …
of disease and conditions difficult to address with single, defined compounds. However their …
Strong Elastic Protein Nanosheets Enable the Culture and Differentiation of Induced Pluripotent Stem Cells on Microdroplets
E Mojares, A Chrysanthou, JE Gautrot - bioRxiv, 2023 - biorxiv.org
Advances in stem cell technologies, revolutionising regenerative therapies and advanced in
vitro testing, require novel cell manufacturing pipelines able to cope with scale up and …
vitro testing, require novel cell manufacturing pipelines able to cope with scale up and …
Biomimetic Artificial Bone Marrow Niches for the Scale Up of Hematopoietic Stem Cells
J Gautrot, M Bosch-Fortea, D Marciano - 2023 - researchsquare.com
Hematopoietic stem cell (HSC) transplantation to treat haematological disorders is greatly
restricted by poor cell availability. Ex vivo expansion of HSCs as a strategy to overcome this …
restricted by poor cell availability. Ex vivo expansion of HSCs as a strategy to overcome this …
The mechanical anisotropy of adipose tissues regulates ovarian cancer invasion
J Gonzalez-Molina, P Nabili, D Marciano, S Abdelnabi… - bioRxiv, 2024 - biorxiv.org
High-grade serous ovarian cancer, the most common and aggressive form of ovarian
cancer, generally metastasises to visceral adipose tissues. In these tissues, the extracellular …
cancer, generally metastasises to visceral adipose tissues. In these tissues, the extracellular …