Nucleic-acid aptamers have the molecular recognition properties of antibodies, and can be
isolated robotically for high-throughput applications in diagnostics, research and …

Aptamers are in vitro selected DNA or RNA molecules that are capable of binding a wide
range of nucleic and non-nucleic acid molecules with high affinity and specificity. They have …

An important current issue of modern molecular medicine and biotechnology is the search
for new approaches to early diagnostic assays and adequate therapy of infectious diseases …

Single-stranded DNA or RNA aptamer molecules have usually been selected against
purified target molecules. To eliminate the need of purifying target molecules on the cell …

Recent times have experienced more than ever the impact of viral infections in humans.
Viral infections are known to cause diseases not only in humans but also in plants and …

The C-terminal portion of hepatitis C virus (HCV) nonstructural protein 3 (NS3) forms a three
domain polypeptide that possesses the ability to travel along RNA or single-stranded DNA …

DNA aptamers specifically recognizing microbial cells and viruses have a range of analytical
and therapeutic applications. This article describes recent advances in the development of …

Appropriate diagnosis is the key factor for treatment of viral diseases. Time is the most
important factor in rapidly developing and epidemiologically dangerous diseases, such as …

Helicases are ubiquitous motor proteins that separate and/or rearrange nucleic acid
duplexes in reactions fueled by adenosine triphosphate (ATP) hydrolysis. Helicases …

Viral infections cause a host of fatal diseases and seriously affect every form of life from
bacteria to humans. Although most viral infections can receive appropriate treatment thereby …