Third-generation sequencing in the clinical laboratory: exploring the advantages and challenges of nanopore sequencing
LM Petersen, IW Martin, WE Moschetti… - Journal of clinical …, 2019 - Am Soc Microbiol
Metagenomic sequencing for infectious disease diagnostics is an important tool that holds
promise for use in the clinical laboratory. Challenges for implementation so far include high …
promise for use in the clinical laboratory. Challenges for implementation so far include high …
DNA electrochemistry and electrochemical sensors for nucleic acids
EE Ferapontova - Annual review of analytical chemistry, 2018 - annualreviews.org
Sensitive, specific, and fast analysis of nucleic acids (NAs) is strongly needed in medicine,
environmental science, biodefence, and agriculture for the study of bacterial contamination …
environmental science, biodefence, and agriculture for the study of bacterial contamination …
[HTML][HTML] Scedosporium and Lomentospora infections: contemporary microbiological tools for the diagnosis of invasive disease
Scedosporium/Lomentospora fungi are increasingly recognized pathogens. As these fungi
are resistant to many antifungal agents, early diagnosis is essential for initiating targeted …
are resistant to many antifungal agents, early diagnosis is essential for initiating targeted …
Scedosporiosis and lomentosporiosis: Modern perspectives on these difficult-to-treat rare mold infections
CF Neoh, SCA Chen, F Lanternier, SY Tio… - Clinical Microbiology …, 2024 - Am Soc Microbiol
SUMMARY Although Scedosporium species and Lomentospora prolificans are uncommon
causes of invasive fungal diseases (IFDs), these infections are associated with high mortality …
causes of invasive fungal diseases (IFDs), these infections are associated with high mortality …
Applications and potentials of nanopore sequencing in the (epi) genome and (epi) transcriptome era
Summary The Human Genome Project opened an era of (epi) genomic research, and also
provided a platform for the development of new sequencing technologies. During and after …
provided a platform for the development of new sequencing technologies. During and after …
Long-reads-based metagenomics in clinical diagnosis with a special focus on fungal infections
Identification of the causative infectious agent is essential in the management of infectious
diseases, with the ideal diagnostic method being rapid, accurate, and informative, while …
diseases, with the ideal diagnostic method being rapid, accurate, and informative, while …
Insights into the social life and obscure side of Scedosporium/Lomentospora species: ubiquitous, emerging and multidrug-resistant opportunistic pathogens
TP Mello, VCB Bittencourt, LC Liporagi-Lopes… - Fungal Biology …, 2019 - Elsevier
The undeniable relevance of fungal infections caused by both yeasts and molds has
considerably augmented over the last four decades, becoming a serious health public …
considerably augmented over the last four decades, becoming a serious health public …
Antifungal susceptibility profiles and drug resistance mechanisms of clinical Lomentospora prolificans isolates
Y Wu, N Grossman, M Totten, W Memon… - Antimicrobial agents …, 2020 - Am Soc Microbiol
Lomentospora prolificans is an opportunistic fungal pathogen with low susceptibility to
current antifungal drugs. Here, we tested the in vitro susceptibility of 8 drugs against 42 …
current antifungal drugs. Here, we tested the in vitro susceptibility of 8 drugs against 42 …
The genomes of Scedosporium between environmental challenges and opportunism
Emerging fungal pathogens are a global challenge for humankind. Many efforts have been
made to understand the mechanisms underlying pathogenicity in bacteria, and OMICs …
made to understand the mechanisms underlying pathogenicity in bacteria, and OMICs …
[HTML][HTML] Yeast metagenomics: analytical challenges in the analysis of the eukaryotic microbiome
Even if their impact is often underestimated, yeasts and yeast-like fungi represent the most
prevalent eukaryotic members of microbial communities on Earth. They play numerous roles …
prevalent eukaryotic members of microbial communities on Earth. They play numerous roles …