Selenium-binding protein 1 (SBP1) is a highly conserved protein that covalently binds
selenium. SBP1 may play important roles in several fundamental physiological functions …

Thyroid transcription factor‐1 (TTF‐1/NKx2. 1) is a member of the NKx2 tissue‐specific
transcription factor family, which is expressed in thyroid follicle, parathyroid gland, alveolar …

Background Lung squamous cell carcinoma (LUSC) patients are often diagnosed at an
advanced stage and have poor prognoses. Thus, identifying novel biomarkers for the LUSC …

Pulmonary arterial hypertension (PAH) is a chronic cardiopulmonary syndrome with high
pulmonary vascular load and eventually causing RV heart failure even death. However, the …

Brain metastasis is a significant cause of morbidity and mortality in multiple cancer types and
represents an unmet clinical need. The mechanisms that mediate metastatic cancer growth …

Hydrogen sulfide (H2S), a mammalian gasotransmitter, is involved in the regulation of a
variety of fundamental processes including intracellular signaling, cellular bioenergetics, cell …

In order to cope with increased demands for energy and metabolites as well as to enhance
stress resilience, tumor cells develop various metabolic adaptations, representing a …

Cancer arises from a single cell through a series of acquired mutations and epigenetic
alterations. Tumors gradually develop into a complex tissue comprised of phenotypically …

Background Selenium is an essential trace element in the human body. In epidemiological
and clinical studies, Se supplementation significantly reduced the incidence of lung cancer …

Lung adenocarcinoma (LUAD) is often diagnosed at an advanced stage, so it is necessary
to identify potential biomarkers for the early diagnosis and prognosis of LUAD. In our study …