Topographic maps are a fundamental organizational feature of axonal connections in the
brain. A prominent model for studying axial polarity and topographic map development is the …

The ventromedial nucleus of the hypothalamus (VMH) is important in the regulation of
female sexual behavior, feeding, energy balance, and cardiovascular function. It is a highly …

Brain function requires precisely orchestrated connectivity between neurons. Establishment
of these connections is believed to require signals secreted from outgrowing axons, followed …

Pallial and subpallial morphological subdivisions of the developing chicken telencephalon
were examined by means of gene markers, compared with their expression pattern in the …

During development of the neocortex, the marginal zone (layer I) and the subplate (layer VII)
are the first layers to form from a primordial plexiform neoropil. The cortical plate (layers II …

We have examined the genetic mechanisms that regulate dorsal-ventral identity in the
embryonic mouse telencephalon and, in particular, the specification of progenitors in the …

The Pax6 gene encodes a transcription factor with a restricted expression in the ventricular
zone of the pallium and subpallium. We tested whether the function of Pax6 is necessary for …

In vertebrates, specification of anteroposterior (A/P) and left–right (L/R) axes depends on
TGFβ-related signals, including Nodal, Lefty, and BMPs. Endoproteolytic maturation of these …

The hypothalamus is the central regulator of systemic energy homeostasis, and its
dysfunction can result in extreme body weight alterations. Insights into the complex cellular …

The novel homeobox-containing gene Vax1, a member of the Emx/Not gene family, is
specifically expressed in the developing basal forebrain and optic nerve. Here, we show that …