The sense of smell is interrelated with psychosocial functioning. Olfactory disorders often
decrease quality of life but treatment options for people with olfactory loss are limited …

The integration of adult-born neurons into the circuitry of the adult hippocampus suggests an
important role for adult hippocampal neurogenesis in learning and memory, but its specific …

An ageing world population has fuelled interest in regenerative remedies that may stem
declining organ function and maintain fitness. Unanswered is whether elimination of intrinsic …

At the present time, no viable treatment exists for cognitive and olfactory deficits in Down
syndrome (DS). We show in a DS model (Ts65Dn mice) that these progressive …

While adult-born neurons in the olfactory bulb (OB) and the dentate gyrus (DG) subregion of
the hippocampus have fundamentally different properties, they may have more in common …

In this review, we consider the evidence that a reduction in neurogenesis underlies aging-
related cognitive deficits and impairments in disorders such as Alzheimer's disease (AD) …

The adult mammalian brain contains a population of neural stem cells that can give rise to
neurons, astrocytes, and oligodendrocytes and are thought to be involved in certain forms of …

In mammals, new neurons are recruited into restricted brain areas throughout life. Adult-born
neurons produced in the subventricular zone of the lateral ventricle migrate rostrally towards …

Most organisms use their olfactory system to detect and analyze chemical cues from the
external world to guide essential behaviors. From worms to vertebrates, chemicals are …

Thousand of local interneurons reach the olfactory bulb of adult rodents every day, but the
functional effect of this process remains elusive. By selectively expressing channelrhodopsin …