Chemotherapy is an important therapeutic approach for the treatment of cancer. Currently,
many anticancer drugs are available in the market that plays an important role in cancer …

Background: Cancer is the first or second leading cause of premature death in 134 of 183
countries in the world. 1, 3, 4-Oxadiazoles are five membered heterocyclic rings containing …

Periodontal disease (PD) is multifactorial oral disease that damages tooth-supporting tissue.
PD treatment includes proper oral hygiene, deep cleaning, antibiotics therapy, and surgery …

Oxadiazoles are five-membered heterocyclic molecules possessing two carbon, two
nitrogen, and one oxygen atom. They exist in four regioisomeric forms and established their …

Due to chronic inflammation, elevated cyclooxygenase (COX-2) level leads to
tumorigenesis, proliferation, invasion, angiogenesis and metastasis. Therefore, suppression …

In this report, a series of chalcone-benzoxadiazole hybrids; 3a–3g were synthesized by
substituting in phenyl ring C 4′ with–OCH 3,-CH 3,-F,-Cl,-Br and C 3′ with-NO 2 …

In this study a series of benzimidazolium salts and silver-benimidazol-2-ylidene complexes
were synthesized. The obtained silver complexes were converted into Ru (II)-benimidazol-2 …

Design, Synthesis and Pharmacological Evaluation of Some C₃ Heterocyclic-Substituted
Ciprofloxacin Derivatives as Chimeric Antitubercular Agents Toggle navigation J-STAGE home …

Hybrid pharmacophoric approach (HPA) has gained great consideration in recent years as it
leads to the production of a novel hybrid molecule with a better target ability. Due to the …

A novel class of chalcones were designed and synthesized by the condensation of benzo [2,
3-c][1],[2],[5] oxadiazole-4-carbaldehyde with substituted acetophenones. All the …