[HTML][HTML] The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions

TJ Littlejohns, J Holliday, LM Gibson, S Garratt… - Nature …, 2020 - nature.com
UK Biobank is a population-based cohort of half a million participants aged 40–69 years
recruited between 2006 and 2010. In 2014, UK Biobank started the world's largest multi …

United Kingdom Biobank (UK Biobank) JACC Focus Seminar 6/8

R Caleyachetty, T Littlejohns, B Lacey, J Bešević… - Journal of the American …, 2021 - jacc.org
An increasing number of people are now living with cardiovascular disease (CVD), with
concomitant CVD-related hospitalizations, operations, and prescriptions. To ultimately …

[HTML][HTML] Analysis of cardiac magnetic resonance imaging in 36,000 individuals yields genetic insights into dilated cardiomyopathy

JP Pirruccello, A Bick, M Wang, M Chaffin… - Nature …, 2020 - nature.com
Dilated cardiomyopathy (DCM) is an important cause of heart failure and the leading
indication for heart transplantation. Many rare genetic variants have been associated with …

Improving explainability of deep neural network-based electrocardiogram interpretation using variational auto-encoders

RR van de Leur, MN Bos, K Taha… - … Heart Journal-Digital …, 2022 - academic.oup.com
Abstract Aims Deep neural networks (DNNs) perform excellently in interpreting
electrocardiograms (ECGs), both for conventional ECG interpretation and for novel …

Light to moderate coffee consumption is associated with lower risk of death: a UK Biobank study

J Simon, K Fung, Z Raisi-Estabragh… - European Journal of …, 2022 - academic.oup.com
Aims To study the association of daily coffee consumption with all-cause and cardiovascular
(CV) mortality and major CV outcomes. In a subgroup of participants who underwent …

Association between ambient air pollution and cardiac morpho-functional phenotypes: insights from the UK Biobank Population Imaging Study

N Aung, MM Sanghvi, F Zemrak, AM Lee, JA Cooper… - Circulation, 2018 - Am Heart Assoc
Background: Exposure to ambient air pollution is strongly associated with increased
cardiovascular morbidity and mortality. Little is known about the influence of air pollutants on …

[HTML][HTML] On zebrafish disease models and matters of the heart

P Giardoglou, D Beis - Biomedicines, 2019 - mdpi.com
Coronary artery disease (CAD) is the leading form of cardiovascular disease (CVD), which is
the primary cause of mortality worldwide. It is a complex disease with genetic and …

[HTML][HTML] Radiomics signatures of cardiovascular risk factors in cardiac MRI: results from the UK biobank

I Cetin, Z Raisi-Estabragh, SE Petersen… - Frontiers in …, 2020 - frontiersin.org
Cardiovascular magnetic resonance (CMR) radiomics is a novel technique for advanced
cardiac image phenotyping by analyzing multiple quantifiers of shape and tissue texture. In …

Left atrial structure and function are associated with cardiovascular outcomes independent of left ventricular measures: a UK Biobank CMR study

Z Raisi-Estabragh, C McCracken… - European Heart …, 2022 - academic.oup.com
Aims We evaluated the associations of left atrial (LA) structure and function with prevalent
and incident cardiovascular disease (CVD), independent of left ventricular (LV) metrics, in …

Cardiovascular magnetic resonance imaging in the UK Biobank: a major international health research resource

Z Raisi-Estabragh, NC Harvey… - European Heart …, 2021 - academic.oup.com
Abstract The UK Biobank (UKB) is a health research resource of major international
importance, incorporating comprehensive characterization of> 500 000 men and women …