The genetic epidemiology of substance use disorder: A review
EC Prom-Wormley, J Ebejer, DM Dick… - Drug and alcohol …, 2017 - Elsevier
Background Substance use disorder (SUD) remains a significant public health issue. A
greater understanding of how genes and environment interact to regulate phenotypes …
greater understanding of how genes and environment interact to regulate phenotypes …
Emerging role of epigenetic mechanisms in alcohol addiction
TDM Berkel, SC Pandey - Alcoholism: Clinical and …, 2017 - Wiley Online Library
Alcohol use disorder (AUD) is a complex brain disorder with an array of persistent
behavioral and neurochemical manifestations. Both genetic and environmental factors are …
behavioral and neurochemical manifestations. Both genetic and environmental factors are …
Epigenetics of alcohol use disorder—A review of recent advances in DNA methylation profiling
MJ Longley, J Lee, J Jung, FW Lohoff - Addiction biology, 2021 - Wiley Online Library
Alcohol use disorder (AUD) is a major contributor to morbidity and mortality worldwide.
Although there is a heritable component, the etiology of AUD is complex and can involve …
Although there is a heritable component, the etiology of AUD is complex and can involve …
Current and future prospects for epigenetic biomarkers of substance use disorders
Substance abuse has an enormous impact on economic and quality of life measures
throughout the world. In more developed countries, overutilization of the most common forms …
throughout the world. In more developed countries, overutilization of the most common forms …
[HTML][HTML] Forensic DNA methylation profiling from evidence material for investigative leads
HY Lee, SD Lee, KJ Shin - BMB reports, 2016 - ncbi.nlm.nih.gov
DNA methylation is emerging as an attractive marker providing investigative leads to solve
crimes in forensic genetics. The identification of body fluids that utilizes tissue-specific DNA …
crimes in forensic genetics. The identification of body fluids that utilizes tissue-specific DNA …
The dopamine transporter role in psychiatric phenotypes
A Salatino‐Oliveira, LA Rohde… - American Journal of …, 2018 - Wiley Online Library
The dopamine transporter (DAT) is one of the most relevant and investigated
neurotransmitter transporters. DAT is a plasma membrane protein which plays a …
neurotransmitter transporters. DAT is a plasma membrane protein which plays a …
Children's DAT1 polymorphism moderates the relationship between parents' psychological profiles, children's DAT methylation, and their emotional/behavioral …
Parental psychopathological risk is considered as one of the most crucial features
associated with epigenetic modifications in offspring, which in turn are thought to be related …
associated with epigenetic modifications in offspring, which in turn are thought to be related …
DNA methylation and alcohol use disorders: Progress and challenges
H Zhang, J Gelernter - The American journal on addictions, 2017 - Wiley Online Library
Background and Objectives Risk for alcohol use disorders (AUDs) is influenced by gene–
environment interactions. Environmental factors can affect gene expression through …
environment interactions. Environmental factors can affect gene expression through …
DNA methylation signatures: Biomarkers of drug and alcohol abuse
DNA sequence is a powerful tool that can be used for an individual's identification and
investigation of various abnormalities in the genome. However, recent studies have …
investigation of various abnormalities in the genome. However, recent studies have …
Epigenetic Analysis of the Dopamine Transporter Gene DAT1 with a Focus on Personality Traits in Athletes
K Humińska-Lisowska, K Chmielowiec… - International Journal of …, 2023 - mdpi.com
Human phenotypes (traits) are determined by the selective use of a person's unique
genotype (DNA sequence), following exposure to environmental stimuli, such as exercise …
genotype (DNA sequence), following exposure to environmental stimuli, such as exercise …