Despite recent advances, cytomegalovirus (CMV) infections remain one of the most common
complications affecting solid organ transplant recipients, conveying higher risks of …

In recent decades, drugs used to treat malaria infection have been shown to be beneficial for
many other diseases, including viral infections. In particular, they have received special …

Natural products represent valuable chemical scaffolds for drug development. A recent
success story in this context was artemisinin, which is not only active against malaria but …

Artemisinins are a family of sesquiterpene lactones originally derived from the sweet
wormwood (Artemisia annua). Beyond their well‐characterized role as frontline antimalarial …

The prevention and treatment of human cytomegalovirus (HCMV) infections is based on the
use of antiviral agents that currently target the viral DNA polymerase and that may cause …

Background Nearly a year into the COVID-19 pandemic, we still lack effective anti-SARS-
CoV-2 drugs with substantial impact on mortality rates except for dexamethasone. As the …

The human cytomegalovirus (HCMV), one of eight human herpesviruses, establishes
lifelong latent infections in most people worldwide. Primary or reactivated HCMV infections …

Human cytomegalovirus (HCMV) is one of the main causes of serious complications in
immunocompromised patients and after congenital infection. There are currently drugs …

Background Artesunate, as a semi-synthetic artemisinin derivative of sesquiterpene lactone,
is widely used in clinical antimalarial treatment due to its endoperoxide group. Recent …

The human cytomegalovirus (CMV) UL97 kinase inhibitor maribavir is in Phase III clinical
trials as antiviral therapy, including use for infections refractory or resistant to standard …