Meiotic recombination: insights into its mechanisms and its role in human reproduction with a special focus on non-obstructive azoospermia

C Xie, W Wang, C Tu, L Meng, G Lu… - Human reproduction …, 2022 - academic.oup.com
BACKGROUND Meiosis is an essential stage in the life cycle of sexually reproducing
species, underlying formation of haploid gametes and serving as the basis of genetic …

The cohesin complex in mammalian meiosis

K Ishiguro - Genes to Cells, 2019 - Wiley Online Library
Cohesin is an evolutionary conserved multi‐protein complex that plays a pivotal role in
chromosome dynamics. It plays a role both in sister chromatid cohesion and in establishing …

Chromosome organization in early meiotic prophase

C Grey, B De Massy - Frontiers in cell and developmental biology, 2021 - frontiersin.org
One of the most fascinating aspects of meiosis is the extensive reorganization of the genome
at the prophase of the first meiotic division (prophase I). The first steps of this reorganization …

Meiotic chromosome structure, the synaptonemal complex, and infertility

IR Adams, OR Davies - Annual Review of Genomics and …, 2023 - annualreviews.org
In meiosis, homologous chromosome synapsis is mediated by a supramolecular protein
structure, the synaptonemal complex (SC), that assembles between homologous …

Mutations in the stromal antigen 3 (STAG3) gene cause male infertility due to meiotic arrest

N Van Der Bijl, A Röpke, U Biswas, M Wöste… - Human …, 2019 - academic.oup.com
STUDY QUESTION Are sequence variants in the stromal antigen 3 (STAG3) gene a cause
for non-obstructive azoospermia (NOA) in infertile human males? SUMMARY ANSWER …

The ubiquitin–proteasome system regulates meiotic chromosome organization

X Yang, M Song, Y Wang, T Tan… - Proceedings of the …, 2022 - National Acad Sciences
Meiotic crossover (CO) recombination is tightly regulated by chromosome architecture to
ensure faithful chromosome segregation and to reshuffle alleles between parental …

[HTML][HTML] ZFP541 maintains the repression of pre-pachytene transcriptional programs and promotes male meiosis progression

J Xu, J Gao, J Liu, X Huang, H Zhang, A Ma, J Ye… - Cell Reports, 2022 - cell.com
The DSB machinery, which induces the programmed DNA double-strand breaks (DSBs) in
the leptotene and zygotene stages during meiosis, is suppressed before the onset of the …

Disruption of REC8 in Meiosis I led to watermelon seedless

L Cao, C Li, H Li, Z Wang, Y Jiang, Y Guo, P Sun… - Plant Science, 2022 - Elsevier
In triploid watermelon (Citrullus lanatus), the homologous chromosomes of germ cells are
disorder during meiosis, resulting in the failure of seeds formation and producing seedless …

The multiple facets of the SMC1A gene

A Musio - Gene, 2020 - Elsevier
Abstract Structural Maintenance of Chromosomes (SMCs) are part of a large family of ring
complexes that participates in a number of DNA transactions. Among SMCs, SMC1A gene is …

Meiotic chromosomes in motion: a perspective from Mus musculus and Caenorhabditis elegans

J Link, V Jantsch - Chromosoma, 2019 - Springer
Vigorous chromosome movement during the extended prophase of the first meiotic division
is conserved in most eukaryotes. The movement is crucial for the faithful segregation of …