HER2 (Human Epidermal Growth Factor Receptor 2)-positive breast cancer is characterized
by amplification of the HER2 gene and is associated with more aggressive tumor growth …

The aim of this review was to assess recent progress in targeted radionuclide tumor therapy,
focusing on the best delivery strategies. A literature search was conducted in PubMed, Web …

Purpose The unique structure of nanobodies is advantageous for the development of
radiopharmaceuticals for nuclear medicine. Nanobodies targeted to human epidermal …

Purpose FAP is a membrane-bound protease under investigation as a pan-cancer target,
given its high levels in tumors but limited expression in normal tissues. FAP-2286 is a …

Radionuclides internal radiotherapy (RIT) is a clinically powerful method for cancer
treatment, but still poses unsatisfactory therapeutic outcomes due to the hypoxic …

Background Breast cancer is the most prevalent malignant tumor among women, with
hormone receptor-positive cases constituting 70%. Fulvestrant, an antagonist for these …

Simple Summary Low-dose radiation delivered by radionuclides stimulates an immune
response against cancer. We hypothesize that this type of low-dose radiation can potentiate …

Simple Summary Targeted alpha therapy (TαT) has revolutionized cancer treatment by
delivering high-energy but short-range particles directly to tumor cells. The discovery of …

Radionuclide-mediated diagnosis and therapy have emerged as effective and low-risk
approaches to treating breast cancer. Compared to traditional anatomic imaging techniques …

Radionuclide antibody conjugate (RAC) is a promising diagnostic and therapeutic tool. It
combines radionuclides and antibodies by connecting arms and chelating agents, offering …