Ferroptosis: machinery and regulation
Ferroptosis is an iron-dependent, non-apoptotic form of regulated cell death caused by lipid
peroxidation, which is controlled by integrated oxidation and antioxidant systems. The iron …
peroxidation, which is controlled by integrated oxidation and antioxidant systems. The iron …
Programmed cell death tunes tumor immunity
The demise of cells in various ways enables the body to clear unwanted cells. Studies over
the years revealed distinctive molecular mechanisms and functional consequences of …
the years revealed distinctive molecular mechanisms and functional consequences of …
Ferroptosis mechanisms involved in neurodegenerative diseases
CO Reichert, FA de Freitas, J Sampaio-Silva… - International journal of …, 2020 - mdpi.com
Ferroptosis is a type of cell death that was described less than a decade ago. It is caused by
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …
the excess of free intracellular iron that leads to lipid (hydro) peroxidation. Iron is essential …
Oxidative stress: a key modulator in neurodegenerative diseases
Oxidative stress is proposed as a regulatory element in ageing and various neurological
disorders. The excess of oxidants causes a reduction of antioxidants, which in turn produce …
disorders. The excess of oxidants causes a reduction of antioxidants, which in turn produce …
Ferroptosis and cancer: mitochondria meet the “iron maiden” cell death
Ferroptosis is a new type of oxidative regulated cell death (RCD) driven by iron-dependent
lipid peroxidation. As major sites of iron utilization and master regulators of oxidative …
lipid peroxidation. As major sites of iron utilization and master regulators of oxidative …
FTH1 inhibits ferroptosis through ferritinophagy in the 6-OHDA model of Parkinson's disease
Y Tian, J Lu, X Hao, H Li, G Zhang, X Liu, X Li, C Zhao… - …, 2020 - Springer
Parkinson's disease (PD) is a neurodegenerative disorder characterized by degeneration of
dopaminergic neurons associated with dysregulation of iron homeostasis in the brain …
dopaminergic neurons associated with dysregulation of iron homeostasis in the brain …
Fighting age-related orthopedic diseases: focusing on ferroptosis
Q Ru, Y Li, W Xie, Y Ding, L Chen, G Xu, Y Wu… - Bone research, 2023 - nature.com
Ferroptosis, a unique type of cell death, is characterized by iron-dependent accumulation
and lipid peroxidation. It is closely related to multiple biological processes, including iron …
and lipid peroxidation. It is closely related to multiple biological processes, including iron …
[HTML][HTML] Oxidative stress: role of physical exercise and antioxidant nutraceuticals in adulthood and aging
C Simioni, G Zauli, AM Martelli, M Vitale, G Sacchetti… - Oncotarget, 2018 - ncbi.nlm.nih.gov
Physical exercise is considered to be one of the beneficial factors of a proper lifestyle and is
nowadays seen as an indispensable element for good health, able to lower the risk of …
nowadays seen as an indispensable element for good health, able to lower the risk of …
Ferroptosis and its role in diverse brain diseases
Ferroptosis is a recently identified, iron-regulated, non-apoptotic form of cell death. It is
characterized by cellular accumulation of lipid reactive oxygen species that ultimately leads …
characterized by cellular accumulation of lipid reactive oxygen species that ultimately leads …
Arsenic induces pancreatic dysfunction and ferroptosis via mitochondrial ROS-autophagy-lysosomal pathway
S Wei, T Qiu, X Yao, N Wang, L Jiang, X Jia… - Journal of hazardous …, 2020 - Elsevier
Chronic arsenic exposure is a significantly risk factor for pancreatic dysfunction and type 2
diabetes (T2D). Ferroptosis is a newly identified iron-dependent form of oxidative cell death …
diabetes (T2D). Ferroptosis is a newly identified iron-dependent form of oxidative cell death …