Abstract Background Leprosy or Hansen's disease is a chronic infection caused by
Mycobacterium leprae (M. leprae) or Mycobacterium lepromatosis (M. lepromatosis). In …

Leprosy is caused by Mycobacterium leprae (M. leprae) and M. lepromatosis, an obligate
intracellular organism, and over 200,000 new cases occur every year. M. leprae parasitizes …

Leprosy is an infectious disease that may present different clinical forms depending on host
immune response to Mycobacterium leprae. Several studies have clarified the role of …

Abstract Mannose-capped lipoarabinomannan (ManLAM), present in all members of the
Mycobacterium tuberculosis complex and in other pathogenic Mycobacterium spp, is a high …

Mycobacterium leprae, the causative agent of leprosy, is still actively transmitted in endemic
areas reflected by the fairly stable number of new cases detected each year. Recognizing …

The complement system orchestrates a multi-faceted immune response to the invading
pathogen, Mycobacterium tuberculosis. Macrophages engulf the mycobacterial bacilli …

Background Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative
disease with no available therapy. Components of the innate immune system are activated …

The complement system is a key driver of neuroinflammation. Activation of complement by
all pathways, results in the formation of the anaphylatoxin C5a and the membrane attack …

Mycobacterium leprae (ML) infection causes nerve damage that often leads to permanent
loss of cutaneous sensitivity and limb deformities, but understanding of the pathogenesis of …

Mycobacterial pathogens can be categorized into three broad groups: Mycobacterium
tuberculosis complex causing tuberculosis, M. leprae and M. lepromatosis causing leprosy …