Ferroquine (FQ, SSR97193) is currently the most advanced organometallic drug candidate
and about to complete phase II clinical trials as a treatment for uncomplicated malaria. This …

Aquatic algal communities demonstrated their appeal for diverse industrial applications due
to their vast availability, ease of harvest, lower production costs, and ability to biosynthesize …

Triflic acid‐functionalized silica‐coated magnetic nanoparticles [γ‐Fe2O3@ SiO2‐TfOH]
were readily prepared and identified as an effictive catalyst for the transformation of …

A series of new oxygenated analogues of marine 3‐alkylpyridine alkaloids were prepared
from 3‐pyridinepropanol in few steps and in good yields. The key step for the synthesis of …

The ocean is the origin of life, with a unique ecological environment, which has given birth to
a wealth of marine organisms. The ocean is an important source of biological resources and …

The global spread of multi-drug resistant P. falciparum, P. vivax, and P. malariae strains and
absence of long-term effective vaccine makes chemotherapy the mainstay of malaria control …

The most severe form of malaria is caused by the obligate parasite Plasmodium falciparum.
Orotate phosphoribosyltransferase (OPRTase) is the fifth enzyme in the de novo pyrimidine …

Vector-borne diseases account for 17% of the estimated global burden of all infectious
diseases. While malaria is still the deadliest vector-borne disease, dengue has become the …

Drugs used in the treatment of malaria that is caused by various plasmosium species ie P.
falciparum, P. vivax are most irresistible disease throughout the world. The different …

Atovaquone and Mefloquine hydrochloride are well known anti-malarial drugs. Literature
survey reveals that there was no method available for the selected drug combination. In this …