[HTML][HTML] Biodegradable polymeric nanoparticles for drug delivery to solid tumors
A Gagliardi, E Giuliano, E Venkateswararao… - Frontiers in …, 2021 - frontiersin.org
Advances in nanotechnology have favored the development of novel colloidal formulations
able to modulate the pharmacological and biopharmaceutical properties of drugs. The …
able to modulate the pharmacological and biopharmaceutical properties of drugs. The …
Stealth nanoparticles in oncology: Facing the PEG dilemma
S Zalba, TLM Ten Hagen, C Burgui… - Journal of Controlled …, 2022 - Elsevier
Nanoparticles (Nps) have revolutionized the landscape of many treatments, by modifying not
only pharmacokinetic properties of the encapsulated agent, but also providing a significant …
only pharmacokinetic properties of the encapsulated agent, but also providing a significant …
[HTML][HTML] Sustainable technologies for liposome preparation
L Maja, K Željko, P Mateja - The Journal of Supercritical Fluids, 2020 - Elsevier
Liposome possesses a great number of advantages and therefore they can be used for a
variety of applications. Among other things, they can serve as useful drug carriers in …
variety of applications. Among other things, they can serve as useful drug carriers in …
Lipid nanoparticles (LNPs) for in vivo RNA delivery and their breakthrough technology for future applications
RNA therapeutics show a significant breakthrough for the treatment of otherwise incurable
diseases and genetic disorders by regulating disease-related gene expression. The …
diseases and genetic disorders by regulating disease-related gene expression. The …
Lipid nanoparticles for nucleic acid delivery: Current perspectives
E Samaridou, J Heyes, P Lutwyche - Advanced drug delivery reviews, 2020 - Elsevier
Nucleic Acid (NA) based therapeutics are poised to disrupt modern medicine and augment
traditional pharmaceutics in a meaningful way. However, a key challenge to advancing NA …
traditional pharmaceutics in a meaningful way. However, a key challenge to advancing NA …
Potential use of exosomes as diagnostic biomarkers and in targeted drug delivery: progress in clinical and preclinical applications
MN Huda, M Nafiujjaman, IG Deaguero… - ACS biomaterials …, 2021 - ACS Publications
Exosomes are cell-derived vesicles containing heterogeneous active biomolecules such as
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …
proteins, lipids, mRNAs, receptors, immune regulatory molecules, and nucleic acids. They …
[HTML][HTML] Nanoparticle biodistribution coefficients: A quantitative approach for understanding the tissue distribution of nanoparticles
The objective of this manuscript is to provide quantitative insights into the tissue distribution
of nanoparticles. Published pharmacokinetics of nanoparticles in plasma, tumor and 13 …
of nanoparticles. Published pharmacokinetics of nanoparticles in plasma, tumor and 13 …
[HTML][HTML] Mechanistic understanding of in vivo protein corona formation on polymeric nanoparticles and impact on pharmacokinetics
In vitro incubation of nanomaterials with plasma offer insights on biological interactions, but
cannot fully explain the in vivo fate of nanomaterials. Here, we use a library of polymer …
cannot fully explain the in vivo fate of nanomaterials. Here, we use a library of polymer …
PEGylation as a strategy for improving nanoparticle-based drug and gene delivery
Coating the surface of nanoparticles with polyethylene glycol (PEG), or “PEGylation”, is a
commonly used approach for improving the efficiency of drug and gene delivery to target …
commonly used approach for improving the efficiency of drug and gene delivery to target …
Nanogels: An overview of properties, biomedical applications and obstacles to clinical translation
Nanogels have emerged as a versatile hydrophilic platform for encapsulation of guest
molecules with a capability to respond to external stimuli that can be used for a multitude of …
molecules with a capability to respond to external stimuli that can be used for a multitude of …