mRNA-based cancer therapeutics
Due to the fact that mRNA technology allows the production of diverse vaccines and
treatments in a shorter time frame and with reduced expense compared to conventional …
treatments in a shorter time frame and with reduced expense compared to conventional …
mRNA-based therapeutics: powerful and versatile tools to combat diseases
S Qin, X Tang, Y Chen, K Chen, N Fan… - Signal transduction and …, 2022 - nature.com
The therapeutic use of messenger RNA (mRNA) has fueled great hope to combat a wide
range of incurable diseases. Recent rapid advances in biotechnology and molecular …
range of incurable diseases. Recent rapid advances in biotechnology and molecular …
Advances in COVID-19 mRNA vaccine development
E Fang, X Liu, M Li, Z Zhang, L Song, B Zhu… - Signal transduction and …, 2022 - nature.com
To date, the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …
mRNA vaccines for COVID-19 and diverse diseases
Since its outbreak in late 2019, the novel coronavirus disease 2019 (COVID-19) has spread
to every continent on the planet. The global pandemic has affected human health and …
to every continent on the planet. The global pandemic has affected human health and …
Nanomedicines to deliver mRNA: state of the art and future perspectives
I Gómez-Aguado, J Rodríguez-Castejón… - Nanomaterials, 2020 - mdpi.com
The use of messenger RNA (mRNA) in gene therapy is increasing in recent years, due to its
unique features compared to plasmid DNA: Transient expression, no need to enter into the …
unique features compared to plasmid DNA: Transient expression, no need to enter into the …
[HTML][HTML] An evidence based perspective on mRNA-SARS-CoV-2 vaccine development
The first outbreak of coronavirus disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, Hubei Province …
respiratory syndrome coronavirus 2 (SARS-CoV-2) occurred in Wuhan, Hubei Province …
Nucleic acid vaccines for COVID-19: a paradigm shift in the vaccine development arena
Coronavirus disease, COVID-19, has touched every country globally except five countries
(North Korea, Turkmenistan, Tonga, Tuvalu and Nauru). Vaccination is the most effective …
(North Korea, Turkmenistan, Tonga, Tuvalu and Nauru). Vaccination is the most effective …
Research advances on the stability of mRNA vaccines
F Cheng, Y Wang, Y Bai, Z Liang, Q Mao, D Liu, X Wu… - Viruses, 2023 - mdpi.com
Compared to other vaccines, the inherent properties of messenger RNA (mRNA) vaccines
and their interaction with lipid nanoparticles make them considerably unstable throughout …
and their interaction with lipid nanoparticles make them considerably unstable throughout …
Nucleic acid degradation as barrier to gene delivery: a guide to understand and overcome nuclease activity
Gene therapy is on its way to revolutionize the treatment of both inherited and acquired
diseases, by transferring nucleic acids to correct a disease-causing gene in the target cells …
diseases, by transferring nucleic acids to correct a disease-causing gene in the target cells …
Recent advances and challenges in gene delivery mediated by polyester-based nanoparticles
Gene therapy is a promising approach for the treatment of several diseases, such as chronic
or viral infections, inherited disorders, and cancer. The cellular internalization of exogenous …
or viral infections, inherited disorders, and cancer. The cellular internalization of exogenous …