The transcriptional regulators YAP and TAZ are involved in numerous physiological
processes including organ development, growth, immunity and tissue regeneration. YAP …

Airway basal stem cells (BSCs) in the proximal airways are recognized as resident stem
cells capable of self-renewing and differentiating to virtually every pseudostratified …

Proper lung function relies on the precise balance of specialized epithelial cells that
coordinate to maintain homeostasis. Herein, we describe essential roles for the …

Abstract Background Bronchial premalignant lesions (PMLs) are composed primarily of cells
resembling basal epithelial cells of the airways, which through poorly understood …

Skin cancers are by far the most frequently diagnosed human cancers. The closely related
transcriptional co‐regulator proteins YAP and TAZ (WWTR1) have emerged as important …

Airway hillocks are stratified epithelial structures of unknown function. Hillocks persist for
months and have a unique population of basal stem cells that express genes associated …

SNPs within FAM13A (family with sequence similarity 13 member A) gene are significantly
associated with chronic obstructive pulmonary disease and lung function in genome-wide …

The respiratory system is composed of a multitude of cells that organize to form complex
branched airways that end in alveoli, which respectively function to guide air flow and …

The concurrence of chronic obstructive pulmonary disease (COPD) and lung cancer has
been widely reported and extensively addressed by pulmonologists and oncologists …

Epithelial tissues are vital to the function of most organs, providing critical functions such as
secretion, protection, and absorption. Cells within an epithelial layer must coordinate to …