Current and emerging methods for ovarian cancer screening and diagnostics: a comprehensive review

JM Liberto, SY Chen, IM Shih, TH Wang, TL Wang… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

Heterogeneity and treatment landscape of ovarian carcinoma

AC Veneziani, E Gonzalez-Ochoa, H Alqaisi… - Nature Reviews …, 2023 - nature.com
Ovarian carcinoma is characterized by heterogeneity at the molecular, cellular and
anatomical levels, both spatially and temporally. This heterogeneity affects response to …

Risk reduction and screening of cancer in hereditary breast-ovarian cancer syndromes: ESMO Clinical Practice Guideline☆

C Sessa, J Balmaña, SL Bober… - Annals of …, 2023 - annalsofoncology.org
Hereditary breast and ovarian cancer syndrome (HBOC) is clinically defined by family
history criteria, and molecularly defined by identification of germline pathogenic variants …

Gender-specific counselling of patients with upper tract urothelial carcinoma and Lynch syndrome

C Cerrato, SD Pandolfo, R Autorino, A Panunzio… - World Journal of …, 2023 - Springer
Purpose Lynch syndrome (LS) is an autosomal dominant genetic syndrome resulting in a
wide spectrum of malignancies caused by germline mutations in mismatch repair genes …

Female sexual function evaluation and intraoperative vaginal reconstruction in bladder cancer

P Orji, H Sun, I Isali, S Bell, N Zaorsky, K Mishra… - World Journal of …, 2023 - Springer
RC significantly negatively impacts sexual function (SF) in both men and women. While
significant research resources have been allocated to examine the deleterious effects of …

Managing menopause after cancer

M Hickey, P Basu, J Sassarini, ME Stegmann… - The Lancet, 2024 - thelancet.com
Globally, 9 million women are diagnosed with cancer each year. Breast cancer is the most
commonly diagnosed cancer worldwide, followed by colorectal cancer in high-income …

BRCA1 and Metastasis: Outcome of Defective DNA Repair

R Krishnan, PS Patel, R Hakem - Cancers, 2021 - mdpi.com
Simple Summary BRCA1 has critical functions in accurately repairing double stand breaks
in the DNA through a process known as homologous recombination. BRCA1 also has …

Germline pathogenic variants and genetic counseling by ancestry in patients with epithelial ovarian cancer

TY Sia, A Maio, YM Kemel, KS Arora… - JCO Precision …, 2023 - ascopubs.org
PURPOSE To evaluate rates of germline pathogenic/likely pathogenic variants (PVs) and
genetic counseling by ancestry in patients with epithelial ovarian cancer (EOC). METHODS …

[PDF][PDF] Utility of matrix metalloproteinases in the diagnosis, monitoring and prognosis of ovarian cancer patients

A Kicman, M Niczyporuk, M Kulesza… - Cancer management …, 2022 - Taylor & Francis
Ovarian cancer is one of the most common gynecologic malignancies. It is characterized by
a high mortality rate, which is mainly due to the asymptomatic course of the disease. In light …

Screening and prevention of ovarian cancer

M Sideris, U Menon… - Medical Journal of …, 2024 - Wiley Online Library
Ovarian cancer remains the most lethal gynaecological malignancy with 314 000 cases and
207 000 deaths annually worldwide. Ovarian cancer cases and deaths are predicted to …