Rejection of inappropriate synaptic partners in mouse retina mediated by transcellular FLRT2-UNC5 signaling
CL Prigge, M Dembla, A Sharma, M El-Quessny… - Developmental Cell, 2023 - cell.com
During nervous system development, neurons choose synaptic partners with remarkable
specificity; however, the cell-cell recognition mechanisms governing rejection of …
specificity; however, the cell-cell recognition mechanisms governing rejection of …
Protective effect of carvacrol on liver injury in type 2 diabetic db/db mice
W Zhao, L Chen, H Zhou, C Deng… - Molecular …, 2021 - spandidos-publications.com
The present study aimed to investigate the protective effect of carvacrol on liver injury in
mice with type 2 diabetes mellitus (T2DM) and to assess its potential molecular mechanism …
mice with type 2 diabetes mellitus (T2DM) and to assess its potential molecular mechanism …
The PPARγ agonist pioglitazone produces a female-predominant inhibition of hyperalgesia associated with surgical incision, peripheral nerve injury, and painful …
Pioglitazone, an agonist at peroxisome proliferator-activated receptor gamma, is FDA-
approved for the treatment of insulin resistance in type 2 diabetes. Numerous studies in …
approved for the treatment of insulin resistance in type 2 diabetes. Numerous studies in …
Animal models for type 1 and type 2 diabetes: advantages and limitations
R Singh, M Gholipourmalekabadi… - Frontiers in …, 2024 - frontiersin.org
Diabetes mellitus, commonly referred to as diabetes, is a group of metabolic disorders
characterized by chronic elevation in blood glucose levels, resulting from inadequate insulin …
characterized by chronic elevation in blood glucose levels, resulting from inadequate insulin …
MG53 Does Not Manifest the Development of Diabetes in db/db Mice
MG53 is a member of the TRIM protein family that is predominantly expressed in striated
muscles and participates in cell membrane repair. Controversy exists regarding MG53's role …
muscles and participates in cell membrane repair. Controversy exists regarding MG53's role …
The glucocorticoid receptor as a master regulator of the Müller cell response to diabetic conditions in mice
AM Pfaller, L Kaplan, M Carido, F Grassmann… - Journal of …, 2024 - Springer
Diabetic retinopathy (DR) is considered a primarily microvascular complication of diabetes.
Müller glia cells are at the centre of the retinal neurovascular unit and play a critical role in …
Müller glia cells are at the centre of the retinal neurovascular unit and play a critical role in …
Carvacrol may alleviate vascular inflammation in diabetic db/db mice
W Zhao, C Deng, Q Han, H Xu… - … journal of molecular …, 2020 - spandidos-publications.com
Type 2 diabetes mellitus (T2DM) is associated with chronic low‑grade inflammation.
Carvacrol has been confirmed to possess anti‑inflammatory properties, but its effect on …
Carvacrol has been confirmed to possess anti‑inflammatory properties, but its effect on …
Tetra-Primer Amplification-Refractory Mutation System (ARMS)—PCR for Genotyping Mouse Leptin Gene Mutation
Simple Summary We developed a method to detect a single-point mutation in an obese
gene in a mouse research model. The method is quick, easy to conduct, and suitable for …
gene in a mouse research model. The method is quick, easy to conduct, and suitable for …
Development of heart failure with preserved ejection fraction in type 2 diabetic mice is ameliorated by preserving vascular function
M Otto, L Brabenec, M Müller, S Kintrup… - Life sciences, 2021 - Elsevier
Aims Heart failure with preserved ejection fraction (HFpEF) is associated with endothelial
dysfunction and is frequent in people with type 2 diabetes mellitus. In diabetic patients …
dysfunction and is frequent in people with type 2 diabetes mellitus. In diabetic patients …
Ferulic acid attenuates high glucose-induced apoptosis in retinal pigment epithelium cells and protects retina in db/db mice
D Zhu, W Zou, X Cao, W Xu, Z Lu, Y Zhu, X Hu, J Hu… - PeerJ, 2022 - peerj.com
Background Herein, we aimed to present evidence that Ferulic acid (FA), a phenolic acid,
can alleviate high glucose (HG)-induced retinal pigment epithelium (RPE) cell apoptosis …
can alleviate high glucose (HG)-induced retinal pigment epithelium (RPE) cell apoptosis …