[HTML][HTML] Methamphetamine induced neurotoxic diseases, molecular mechanism, and current treatment strategies

P Shrestha, N Katila, S Lee, JH Seo, JH Jeong… - Biomedicine & …, 2022 - Elsevier
Methamphetamine (MA) is a extremely addictive psychostimulant drug with a significant
abuse potential. Long-term MA exposure can induce neurotoxic effects through oxidative …

The neurobiology of methamphetamine induced psychosis

JH Hsieh, DJ Stein, FM Howells - Frontiers in human neuroscience, 2014 - frontiersin.org
Chronic methamphetamine abuse commonly leads to psychosis, with positive and cognitive
symptoms that are similar to those of schizophrenia. Methamphetamine induced psychosis …

Application of metabolomics to toxicology of drugs of abuse: A mini review of metabolomics approach to acute and chronic toxicity studies

K Zaitsu, Y Hayashi, M Kusano, H Tsuchihashi… - Drug metabolism and …, 2016 - Elsevier
Metabolomics has been widely applied to toxicological fields, especially to elucidate the
mechanism of action of toxicity. In this review, metabolomics application with focus on the …

The common denominators of Parkinson's disease pathogenesis and methamphetamine abuse

B Vincent, M Shukla - Current Neuropharmacology, 2023 - hal.science
The pervasiveness and mortality associated with methamphetamine abuse has doubled
during the past decade suggesting a possible worldwide substance use crisis. Epitomizing …

The role of reactive oxygen species in methamphetamine self‐administration and dopamine release in the nucleus accumbens

EY Jang, CH Yang, DM Hedges, SP Kim… - Addiction …, 2017 - Wiley Online Library
Methamphetamine (METH) markedly increases dopamine (DA) release in the mesolimbic
DA system, which plays an important role in mediating the reinforcing effects of METH …

Untargeted metabolomics analysis by gas chromatography/time‐of‐flight mass spectrometry of human serum from methamphetamine abusers

T Wang, C Xu, S Xu, L Gao, I Blaženović, J Ji… - Addiction …, 2021 - Wiley Online Library
Methamphetamine (METH) abuse has become a global public health problem. However, the
potential mechanisms involving METH‐induced metabolic disorders have thus far remained …

Forensic NMR metabolomics: one more arrow in the quiver

E Locci, G Bazzano, A Chighine, F Locco, E Ferraro… - Metabolomics, 2020 - Springer
Introduction NMR metabolomics is increasingly used in forensics, due to the possibility of
investigating both endogenous metabolic profiles and exogenous molecules that may help …

Metabolic phenotyping of opioid and psychostimulant addiction: A novel approach for biomarker discovery and biochemical understanding of the disorder

G Caspani, V Sebők, N Sultana… - British Journal of …, 2022 - Wiley Online Library
Despite the progress in characterising the pharmacological profile of drugs of abuse, their
precise biochemical impact remains unclear. The metabolome reflects the multifaceted …

The role of oxidative stress in methamphetamine-induced toxicity and sources of variation in the design of animal studies

K McDonnell-Dowling, JP Kelly - Current neuropharmacology, 2017 - ingentaconnect.com
Background: The prevalence of methamphetamine (MA) use has increased in recent years.
In order to assess how this drug produces its effects, both clinical and preclinical studies …

mRNA changes in nucleus accumbens related to methamphetamine addiction in mice

L Zhu, J Li, N Dong, F Guan, Y Liu, D Ma, ELK Goh… - Scientific reports, 2016 - nature.com
Methamphetamine (METH) is a highly addictive psychostimulant that elicits aberrant
changes in the expression of microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) in …