[HTML][HTML] Standards for quantification of EMG and neurography

E Stålberg, H van Dijk, B Falck, J Kimura… - Clinical …, 2019 - Elsevier
This document is an update and extension of ICCN Standards published in 1999. It is the
consensus of experts on the current status of EMG and Neurography methods. A panel of …

Biomarkers in motor neuron disease: a state of the art review

NS Verber, SR Shepheard, M Sassani… - Frontiers in …, 2019 - frontiersin.org
Motor neuron disease can be viewed as an umbrella term describing a heterogeneous
group of conditions, all of which are relentlessly progressive and ultimately fatal. The …

Biomarkers in amyotrophic lateral sclerosis: current status and future prospects

R McMackin, P Bede, C Ingre, A Malaspina… - Nature Reviews …, 2023 - nature.com
Disease heterogeneity in amyotrophic lateral sclerosis poses a substantial challenge in drug
development. Categorization based on clinical features alone can help us predict the …

Estimating motor unit numbers from a CMAP scan: Repeatability study on three muscles at 15 centres

DM Sørensen, H Bostock, A Abrahao, A Alaamel… - Clinical …, 2023 - Elsevier
Objective To assess the repeatability and suitability for multicentre studies of MScanFit motor
unit number estimation (MUNE), which involves modelling compound muscle action …

Safety and efficacy of dimethyl fumarate in ALS: randomised controlled study

S Vucic, RD Henderson, S Mathers… - Annals of Clinical …, 2021 - Wiley Online Library
Objective Neuroinflammation is an important pathogenic mechanism in amyotrophic lateral
sclerosis (ALS), with regulatory T cells (Tregs) mediating a slower rate of disease …

Diagnostic accuracy of nerve excitability and compound muscle action potential scan derived biomarkers in amyotrophic lateral sclerosis

DJL Stikvoort García, B Sleutjes… - European Journal of …, 2023 - Wiley Online Library
Background and purpose The lack of reliable early biomarkers still causes substantial
diagnostic delays in amyotrophic lateral sclerosis (ALS). The aim was to assess the …

[HTML][HTML] The evolving role of surface electromyography in amyotrophic lateral sclerosis: A systematic review

J Bashford, K Mills, C Shaw - Clinical Neurophysiology, 2020 - Elsevier
Objective Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease
that leads to inexorable motor decline and a median survival of three years from symptom …

Assessing inter-rater reproducibility in MScanFit MUNE in a 6-subject, 12-rater “Round Robin” setup

DM Sørensen, H Bostock, M Ballegaard… - Neurophysiologie …, 2022 - Elsevier
Objective To assess the inter-rater reliability of MScanFit MUNE using a “Round Robin”
research design. Methods Twelve raters from different centres examined six healthy study …

Motor unit number index and compound muscle action potential amplitude

H Bostock, AB Jacobsen, H Tankisi - Clinical Neurophysiology, 2019 - Elsevier
Objectives MUNIX (motor unit number index), derived from the compound muscle action
potential (CMAP) and surface EMG interference pattern (SIP) has become popular as a …

A scoping review of current and emerging techniques for evaluation of peripheral nerve health, degeneration, and regeneration: Part 1, neurophysiology

R Mandeville, B Sanchez, B Johnston… - Journal of Neural …, 2023 - iopscience.iop.org
Peripheral neuroregeneration research and therapeutic options are expanding
exponentially. With this expansion comes an increasing need to reliably evaluate and …