Cancer is the most devastating disease and second leading cause of death around the
world. Despite scientific advancements in the diagnosis and treatment of cancer which can …

The present work includes the synthesis of a new series of quinazolin-4 (3 H)-one
compounds (4a–f, 5a–d) as antimicrobial agents. The starting compound, 2 …

The cyclic guanosine monophosphate–adenosine monophosphate synthase–stimulator of
interferon genes–TANK-binding kinase 1–interferon regulating factor 3 (cGAS-STING-TBK1 …

Oleanolic acid (OA) and its derivatives show potent anticancer function. Pancreatic cancer
(PC) is the fourth core motive of cancer‐related deaths worldwide. Epidermal growth factor …

The advent of novel receptor tyrosine kinase inhibitors has provided an important
therapeutic tool for cancer patients. In this study, a series of quinazolinone hydrazide triazole …

A novel series of 6-iodo-2-methylquinazolin-4-(3H)-one derivatives, 3a–n, were synthesized
and evaluated for their in vitro cytotoxic activity. Compounds 3a, 3b, 3d, 3e, and 3h showed …

To find new anti-browning and whitening agents in this study, new series of
isopropylquinazolinone derivatives were designed and synthesized. All derivatives were …

The present study focuses on the synthesis of some 2-methoxyphenylquinazolin-4-one
incorporated chalcone hybrids to evaluate their cytotoxic potential by MTT assay, and their …

Представлен обзор литературных данных о принципах создания мультитаргетных
препаратов и механизмах их действия. Проведен анализ результатов изучения …