Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection

WR García-Niño, C Zazueta - Pharmacological Research, 2015 - Elsevier
Traditional drugs or therapies rarely have effects on regression of chronic liver diseases,
which result in many cases from sustained oxidative stress. In recent years, ellagic acid (EA) …

Role of ellagic acid for the prevention and treatment of liver diseases

V Aishwarya, S Solaipriya… - Phytotherapy …, 2021 - Wiley Online Library
Globally, one of the alarming problems is the prevalence and burden of liver diseases,
which accounts for 2 million cases per year. Chronic liver aetiologies such as hepatitis …

Protective effects of pomegranate (Punica granatum) and its main components against natural and chemical toxic agents: A comprehensive review

A Hosseini, BM Razavi, H Hosseinzadeh - Phytomedicine, 2023 - Elsevier
Background Different chemical toxicants or natural toxins can damage human health
through various routes such as air, water, fruits, foods, and vegetables. Purpose Herbal …

Ellagic acid inhibits cardiac arrhythmias, hypertrophy and hyperlipidaemia during myocardial infarction in rats

MM Kannan, SD Quine - Metabolism, 2013 - Elsevier
OBJECTIVE: The objective was to evaluate the protective effect of ellagic acid against
experimentally induced cardiac arrhythmias, hypertrophy and its association with altered …

Toxic effect of cyclophosphamide on sperm morphology, testicular histology and blood oxidant‐antioxidant balance, and protective roles of lycopene and ellagic acid

AO Çeribaşi, G Türk, M Sönmez… - Basic & Clinical …, 2010 - Wiley Online Library
In this study, the toxic effect of cyclophosphamide (CP) on sperm morphology, testicular
histology and blood oxidant–antioxidant balance, and protective roles of lycopene (LC) and …

Ellagic acid: a logical lead for drug development?

A Shakeri, MR Zirak, A Sahebkar - Current pharmaceutical …, 2018 - ingentaconnect.com
Background: Naturally occurring polyphenols are the subject of increasing attention due to
their potent antioxidant activity and their marked effects on the prevention of various …

Promising remedies for cardiovascular disease: Natural polyphenol ellagic acid and its metabolite urolithins

J Li, R Liao, S Zhang, H Weng, Y Liu, T Tao, F Yu, G Li… - Phytomedicine, 2023 - Elsevier
Background Cardiovascular disease (CVD) is a significant worldwide factor contributing to
human fatality and morbidity. With the increase of incidence rates, it is of concern that there …

Ellagic acid mitigates sodium arsenite-induced renal and hepatic toxicity in male Wistar rats

S Mehrzadi, I Fatemi, AR Malayeri, A Khodadadi… - Pharmacological …, 2018 - Springer
Background The aim of this study was to investigate the effect of ellagic acid (EA) on arsenic-
induced renal and hepatic toxicity in rats. Methods A total number of 35 male Wistar rats …

The cardioprotective potentials and the involved mechanisms of phenolic acids in drug-induced cardiotoxicity

X Liu, R Tian, H Tao, J Wu, L Yang, Y Zhang… - European Journal of …, 2022 - Elsevier
Cardiotoxicity is one of the major safety concerns in the use of drug and is the most common
reason for drug removal from the market. At present, several drugs that have been …

Attenuation of cyclosporine A-induced testicular and spermatozoal damages associated with oxidative stress by ellagic acid

G Türk, M Sönmez, AO Çeribaşı, A Yüce… - International …, 2010 - Elsevier
This study was conducted to investigate the possible protective effect of ellagic acid (EA) on
cyclosporine A (CsA)-induced testicular and spermatozoal damages associated with …