SARS-CoV-2 immunity: review and applications to phase 3 vaccine candidates
GA Poland, IG Ovsyannikova, RB Kennedy - The Lancet, 2020 - thelancet.com
Understanding immune responses to severe acute respiratory syndrome coronavirus 2 is
crucial to understanding disease pathogenesis and the usefulness of bridge therapies, such …
crucial to understanding disease pathogenesis and the usefulness of bridge therapies, such …
COVID-19: Discovery, diagnostics and drug development
T Asselah, D Durantel, E Pasmant, G Lau… - Journal of …, 2021 - Elsevier
Summary Coronavirus disease 2019 (COVID-19) started as an epidemic in Wuhan in 2019,
and has since become a pandemic. Groups from China identified and sequenced the virus …
and has since become a pandemic. Groups from China identified and sequenced the virus …
SARS-CoV-2 Omicron variant shows less efficient replication and fusion activity when compared with Delta variant in TMPRSS2-expressed cells
ABSTRACT The novel SARS-CoV-2 Omicron variant (B. 1.1. 529), first found in early
November 2021, has sparked considerable global concern and it has> 50 mutations, many …
November 2021, has sparked considerable global concern and it has> 50 mutations, many …
SARS-CoV-2 infection rates of antibody-positive compared with antibody-negative health-care workers in England: a large, multicentre, prospective cohort study …
VJ Hall, S Foulkes, A Charlett, A Atti, EJM Monk… - The Lancet, 2021 - thelancet.com
Background Increased understanding of whether individuals who have recovered from
COVID-19 are protected from future SARS-CoV-2 infection is an urgent requirement. We …
COVID-19 are protected from future SARS-CoV-2 infection is an urgent requirement. We …
Assessment of protection against reinfection with SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study
CH Hansen, D Michlmayr, SM Gubbels, K Mølbak… - The lancet, 2021 - thelancet.com
Background The degree to which infection with SARS-CoV-2 confers protection towards
subsequent reinfection is not well described. In 2020, as part of Denmark's extensive, free-of …
subsequent reinfection is not well described. In 2020, as part of Denmark's extensive, free-of …
[HTML][HTML] Increased resistance of SARS-CoV-2 variant P. 1 to antibody neutralization
The emergence of SARS-CoV-2 variants has raised concerns about altered sensitivity to
antibody-mediated immunity. The relative resistance of SARS-CoV-2 variants B. 1.1. 7 and …
antibody-mediated immunity. The relative resistance of SARS-CoV-2 variants B. 1.1. 7 and …
Immunological memory to SARS-CoV-2 assessed for up to 8 months after infection
INTRODUCTION Immunological memory is the basis for durable protective immunity after
infections or vaccinations. Duration of immunological memory after severe acute respiratory …
infections or vaccinations. Duration of immunological memory after severe acute respiratory …
Defining the features and duration of antibody responses to SARS-CoV-2 infection associated with disease severity and outcome
SARS-CoV-2-specific antibodies, particularly those preventing viral spike receptor binding
domain (RBD) interaction with host angiotensin-converting enzyme 2 (ACE2) receptor, can …
domain (RBD) interaction with host angiotensin-converting enzyme 2 (ACE2) receptor, can …
Evolution of immune responses to SARS-CoV-2 in mild-moderate COVID-19
The durability of infection-induced SARS-CoV-2 immunity has major implications for
reinfection and vaccine development. Here, we show a comprehensive profile of antibody, B …
reinfection and vaccine development. Here, we show a comprehensive profile of antibody, B …
Genomic evidence for reinfection with SARS-CoV-2: a case study
RL Tillett, JR Sevinsky, PD Hartley… - The Lancet infectious …, 2021 - thelancet.com
Background The degree of protective immunity conferred by infection with severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently unknown. As such, the …
respiratory syndrome coronavirus 2 (SARS-CoV-2) is currently unknown. As such, the …