[HTML][HTML] Mammalian transient receptor potential TRPA1 channels: from structure to disease
K Talavera, JB Startek, J Alvarez-Collazo… - Physiological …, 2020 - journals.physiology.org
The transient receptor potential ankyrin (TRPA) channels are Ca 2+-permeable nonselective
cation channels remarkably conserved through the animal kingdom. Mammals have only …
cation channels remarkably conserved through the animal kingdom. Mammals have only …
The stomach in health and disease
The stomach is traditionally regarded as a hollow muscular sac that initiates the second
phase of digestion. Yet this simple view ignores the fact that it is the most sophisticated …
phase of digestion. Yet this simple view ignores the fact that it is the most sophisticated …
The enteric nervous system in gastrointestinal disease etiology
AM Holland, AC Bon-Frauches, D Keszthelyi… - Cellular and Molecular …, 2021 - Springer
A highly conserved but convoluted network of neurons and glial cells, the enteric nervous
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …
system (ENS), is positioned along the wall of the gut to coordinate digestive processes and …
Transient receptor potential (TRP) channels: a clinical perspective
Y Kaneko, A Szallasi - British journal of pharmacology, 2014 - Wiley Online Library
Transient receptor potential (TRP) channels are important mediators of sensory signals with
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …
marked effects on cellular functions and signalling pathways. Indeed, mutations in genes …
Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation
L De Petrocellis, P Orlando, AS Moriello… - Acta …, 2012 - Wiley Online Library
Aim: Plant cannabinoids, like Δ9‐tetrahydrocannabinol (THC) and cannabidiol (CBD),
activate/desensitize thermosensitive transient receptor potential (TRP) channels of vanilloid …
activate/desensitize thermosensitive transient receptor potential (TRP) channels of vanilloid …
TRPV1 activation counters diet-induced obesity through sirtuin-1 activation and PRDM-16 deacetylation in brown adipose tissue
P Baskaran, V Krishnan, K Fettel, P Gao… - International Journal of …, 2017 - nature.com
Results: CAP antagonized high-fat diet (HFD)-induced obesity without decreasing energy
intake in mice. HFD suppressed TRPV1 expression and activity in BAT and CAP countered …
intake in mice. HFD suppressed TRPV1 expression and activity in BAT and CAP countered …
TRPV4: a physio and pathophysiologically significant ion channel
T Rosenbaum, M Benítez-Angeles… - International journal of …, 2020 - mdpi.com
Transient Receptor Potential (TRP) channels are a family of ion channels whose members
are distributed among all kinds of animals, from invertebrates to vertebrates. The importance …
are distributed among all kinds of animals, from invertebrates to vertebrates. The importance …
[HTML][HTML] Transient receptor potential (TRP) channels as drug targets for diseases of the digestive system
P Holzer - Pharmacology & therapeutics, 2011 - Elsevier
Approximately 20 of the 30 mammalian transient receptor potential (TRP) channel subunits
are expressed by specific neurons and cells within the alimentary canal. They subserve …
are expressed by specific neurons and cells within the alimentary canal. They subserve …
High expression of transient receptor potential channels in human breast cancer epithelial cells and tissues: correlation with pathological parameters
I Dhennin-Duthille, M Gautier, M Faouzi… - Cellular Physiology and …, 2011 - karger.com
Abstract Background: Transient Receptor Potential (TRP) channels are expressed in many
solid tumors. However, their expression in breast cancer remains largely unknown. Here, we …
solid tumors. However, their expression in breast cancer remains largely unknown. Here, we …
Food choice as a key management strategy for functional gastrointestinal symptoms
PR Gibson, SJ Shepherd - Official journal of the American College …, 2012 - journals.lww.com
Recognition of food components that induce functional gut symptoms in patient's functional
bowel disorders (FBD) has been challenging. Food directly or indirectly provides …
bowel disorders (FBD) has been challenging. Food directly or indirectly provides …