[HTML][HTML] Diagnosis and treatment of therapy-related acute myeloid leukemia

SA Strickland, N Vey - Critical reviews in oncology/hematology, 2022 - Elsevier
Therapy-related acute myeloid leukemia (t-AML), defined as AML arising from prior
cytotoxic, radiation, or immunosuppressive therapy for an unrelated disease, accounts for …

Consensus proposal for revised International Working Group 2023 response criteria for higher-risk myelodysplastic syndromes

AM Zeidan, U Platzbecker… - Blood, The Journal …, 2023 - ashpublications.org
Myelodysplastic syndromes/myelodysplastic neoplasms (MDS) are associated with variable
clinical presentations and outcomes. The initial response criteria developed by the …

Risk-stratified therapy for pediatric acute myeloid leukemia

D Tomizawa, SI Tsujimoto - Cancers, 2023 - mdpi.com
Simple Summary Owing to the 40-year worldwide efforts for improving diagnosis and
therapy for acute myeloid leukemia (AML), the second most common type of leukemia in …

[HTML][HTML] Technical aspects of flow cytometry-based measurable residual disease quantification in acute myeloid leukemia: experience of the European LeukemiaNet …

JM Tettero, S Freeman, V Buecklein, A Venditti… - …, 2022 - journals.lww.com
Measurable residual disease (MRD) quantified by multiparameter flow cytometry (MFC) is a
strong and independent prognostic factor in acute myeloid leukemia (AML). However …

Conditioning intensity and peritransplant flow cytometric MRD dynamics in adult AML

G Paras, LM Morsink, M Othus, F Milano… - Blood, The Journal …, 2022 - ashpublications.org
In acute myeloid leukemia (AML), measurable residual disease (MRD) before or after
allogeneic hematopoietic cell transplantation (HCT) is an established independent indicator …

Posttransplant MRD and T-cell chimerism status predict outcomes in patients who received allografts for AML/MDS

J Loke, N McCarthy, A Jackson, S Siddique… - Blood …, 2023 - ashpublications.org
Allogeneic stem-cell transplant allows for the delivery of curative graft-versus-leukemia
(GVL) in patients with acute myeloid leukemia/myelodysplasia (AML/MDS). Surveillance of T …

Consensus opinion from an international group of experts on measurable residual disease in hairy cell leukemia

F Ravandi, RJ Kreitman, E Tiacci, L Andritsos… - Blood cancer …, 2022 - nature.com
A significant body of literature has been generated related to the detection of measurable
residual disease (MRD) at the time of achieving complete remission (CR) in patients with …

Reproducible measurable residual disease detection by multiparametric flow cytometry in acute myeloid leukemia

MA Röhnert, M Kramer, J Schadt, P Ensel, C Thiede… - Leukemia, 2022 - nature.com
Measurable residual disease (MRD) detected by multiparametric flow cytometry (MFC) is
associated with unfavorable outcome in patients with AML. A simple, broadly applicable …

Achieving MRD negativity in AML: how important is this and how do we get there?

CS Hourigan - Hematology, 2022 - ashpublications.org
Multiple studies have demonstrated that patients with acute myeloid leukemia (AML) who
have measurable residual disease (MRD) detected during or after treatment have higher …

[HTML][HTML] Measurable residual disease-guided therapy in intermediate-risk acute myeloid leukemia patients is a valuable strategy in reducing allogeneic transplantation …

JM Tettero, LL Ngai, C Bachas, DA Breems… - …, 2023 - ncbi.nlm.nih.gov
Treatment of patients with acute myeloid leukemia (AML) fit to receive intensive treatment
and under 65 years of age consists of one or two cycles of high-dose induction (“3+ 7”) …