PEG10 as an oncogene: expression regulatory mechanisms and role in tumor progression

T Xie, S Pan, H Zheng, Z Luo, KM Tembo… - Cancer cell …, 2018 - Springer
Cancer is a major public health problem as one of the leading causes of death worldwide.
Deciphering the molecular regulation mechanisms of tumor progression can make way for …

Promising new strategies for hepatocellular carcinoma

Y Nakamoto - Hepatology Research, 2017 - Wiley Online Library
Hepatocellular carcinoma (HCC) is one of the most common causes of cancer death
worldwide. It usually arises based on a background of chronic liver diseases, defined as the …

EpCAM peptide-primed dendritic cell vaccination confers significant anti-tumor immunity in hepatocellular carcinoma cells

YJ Choi, SJ Park, YS Park, HS Park, KM Yang, K Heo - PloS one, 2018 - journals.plos.org
Cancer stem-like cells (CSCs) may play a key role in tumor initiation, self-renewal,
differentiation, and resistance to current treatments. Dendritic cells (DCs) play a vital role in …

[HTML][HTML] The mononuclear phagocyte system in hepatocellular carcinoma

DR Qiao, GY Shan, S Wang, JY Cheng… - World Journal of …, 2022 - ncbi.nlm.nih.gov
The mononuclear phagocyte system (MPS) consists of monocytes, dendritic cells and
macrophages, which play vital roles in innate immune defense against cancer …

Human IP10-scFv and DC-induced CTL synergistically inhibit the growth of glioma in a xenograft model

X Wang, FC Zhang, HY Zhao, XL Lu, Y Sun, ZY Xiong… - Tumor Biology, 2014 - Springer
The epidermal growth factor receptor (EGFR) mutant of EGFRvIII is highly expressed in
glioma cells, and the EGFRvIII-specific dendritic cell (DC)-induced tumor antigen-specific …

PEG10 is imperative for TGF-β1-induced epithelial‑mesenchymal transition in hepatocellular carcinoma

M Zhang, C Sui, B Dai, W Shen, J Lu… - Oncology …, 2017 - spandidos-publications.com
Substantial evidence indicates that transforming growth factor-beta 1 (TGF-β1) plays a vital
role in epithelial-mesenchymal transition (EMT). PEG10 has been shown involved in …

Engineered dendritic cells for gastrointestinal tumor immunotherapy: opportunities in translational research

A Bhargava, D Mishra, S Banerjee… - Journal of Drug …, 2013 - Taylor & Francis
Gastrointestinal (GI) malignancies are one of the most frequently occurring tumors found
worldwide. Surgery remains the primary treatment for most solid tumors and adjuvant …

Recombinant Mammaglobin A Adenovirus-Infected Dendritic Cells Induce Mammaglobin A-Specific CD8+ Cytotoxic T Lymphocytes against Breast Cancer Cells In …

H Cui, W Zhang, W Hu, K Liu, T Wang, N Ma, X Liu… - PLoS …, 2013 - journals.plos.org
Mammaglobin A (MGBA) is a novel breast cancer-associated antigen almost exclusively
over-expressed in primary and metastatic human breast cancers, making it a potential …

肝细胞癌细胞免疫治疗的研究进展

张野, 张明杰, 贾战生 - 临床肝胆病杂志, 2014 - lcgdbzz.org
肝细胞癌(HCC) 的治疗目前主要采用以手术为主, 配合局部放疗和化疗的综合治疗措施,
但多数患者经综合治疗后也容易复发, 缺乏有效的治疗药物和手段, 总体治疗效果并不理想 …

Umbilical cord blood-derived dendritic cells infected by adenovirus for SP17 expression induce antigen-specific cytotoxic T cells against NSCLC cells

Y Liu, X Tian, S Jiang, X Ren, F Liu, J Yang, Y Chen… - Cellular …, 2015 - Elsevier
Abstract Sperm protein 17 (SP17), a cancer/testis antigen, is expressed by non-small cell
lung cancer (NSCLC). This study examined whether dendritic cells (DC) from human …