Anemia as a problem: GP approach

T Milovanovic, S Dragasevic, AN Nikolic… - Digestive …, 2022 - karger.com
Background: Anemia is a presentation of an underlying disease or deficiency. As stated by
the WHO, anemia is defined as hemoglobin (Hb) levels< 12.0 g/dL in women and< 13.0 g/dL …

A taxonomy of early diagnosis research to guide study design and funding prioritisation

E Whitfield, B White, S Denaxas, ME Barclay… - British Journal of …, 2023 - nature.com
Researchers and research funders aiming to improve diagnosis seek to identify if, when,
where, and how earlier diagnosis is possible. This has led to the propagation of research …

Applying a genetic risk score for prostate cancer to men with lower urinary tract symptoms in primary care to predict prostate cancer diagnosis: a cohort study in the UK …

HD Green, SWD Merriel, RA Oram, KS Ruth… - British Journal of …, 2022 - nature.com
Background Prostate cancer is highly heritable, with> 250 common variants associated in
genome-wide association studies. It commonly presents with non-specific lower urinary tract …

Cancer risk in persons with new-onset anaemia: a population-based cohort study in Denmark

A Boennelykke, H Jensen, LSG Østgård, AZ Falborg… - BMC cancer, 2022 - Springer
Background The time interval from first symptom and sign until a cancer diagnosis
significantly affects the prognosis. Therefore, recognising and acting on signs of cancer …

Primary care blood tests before cancer diagnosis: National Cancer Diagnosis Audit data

BM Cranfield, MM Koo, GA Abel, R Swann… - British Journal of …, 2023 - bjgp.org
Background Blood tests can support the diagnostic process in patients with cancer but how
often they are used is unclear. Aim To explore use of common blood tests before cancer …

Pre-Referral Primary Care Blood Tests and Symptom Presentation before Cancer Diagnosis: National Cancer Diagnosis Audit Data

BM Cranfield, GA Abel, R Swann, SF Moore, S McPhail… - Cancers, 2023 - mdpi.com
Simple Summary Blood tests can support decisions by GPs about referring patients who
present with symptoms of possible cancer for specialist assessment. This study analysed …

Investigating WBC margination in different microfluidic geometries: influence of RBC shape and size

S Mane, V Hemadri, S Tripathi - Journal of Micromechanics and …, 2023 - iopscience.iop.org
White blood cells (WBCs) reside close enough to the endothelium vascular wall to detect a
variety of chemical signals and combat bacterial and viral diseases in the human body. It is …

[HTML][HTML] Colorectal cancer in symptomatic patients: How to improve the diagnostic pathway

W Hamilton, SER Bailey - Best Practice & Research Clinical …, 2023 - Elsevier
Even in countries with national screening programmes for colorectal cancer, most cancers
are identified after the patient has developed symptoms. The patients present these …

Underlying cancer risk among patients with fatigue and other vague symptoms: a population-based cohort study in primary care

B White, C Renzi, M Barclay, G Lyratzopoulos - British Journal of General …, 2023 - bjgp.org
Background Presenting to primary care with fatigue is associated with slightly increased
cancer risk, although it is unknown how this varies in the presence of other …

[HTML][HTML] Survival After Wait-and-See Approach in Older Patients With Unexplained Iron Deficiency Anemia in Primary Care: A Practice Evaluation

TC Heil, M van Oostrum, E Holwerda… - Journal of the American …, 2024 - Elsevier
Objectives Guidelines recommend upper and lower gastrointestinal endoscopic evaluation
for patients without a clear physiological explanation for iron deficiency anemia (IDA) …