Sleep is critical for diverse aspects of brain function in animals ranging from invertebrates to
humans. Powerful genetic tools in the fruit fly Drosophila melanogaster have identified—at …

A prominent idea emerging from the study of sleep is that this key behavioural state is
regulated in a complex fashion by ecologically and physiologically relevant environmental …

During sleep, most animal species enter a state of reduced consciousness characterized by
a marked sensory disconnect. Yet some processing of the external world must remain intact …

Sleep is vital for most animals, yet its mechanism and function remain unclear. We found that
permeability of the BBB (blood–brain barrier)—the organ required for the maintenance of …

Behavioral flexibility for appropriate action selection is an advantage when animals are
faced with decisions that will determine their survival or death. In order to arrive at the right …

Humans spend nearly a third of their life sleeping, yet, despite decades of research the
function of sleep still remains a mystery. Sleep has been linked with various biological …

Sleep pressure and sleep depth are key regulators of wake and sleep. Current methods of
measuring these parameters in Drosophila melanogaster have low temporal resolution …

The two‐process model of sleep regulation posits two main processes regulating sleep: the
circadian process controlled by the circadian clock and the homeostatic process that …

Various behavioral and cognitive states exhibit circadian variations in animals across phyla
including Drosophila melanogaster, in which only~ 0.1% of the brain's neurons contain …

Homeostatic control of sleep is typically addressed through mechanical stimulation-induced
forced wakefulness and the measurement of subsequent increases in sleep. A major …