It has been 15 years since the advent of the genome-wide association study (GWAS) era.
Here, we review how this experimental design has realized its promise by facilitating an …

Genome-wide association studies on human behavioural traits are producing large amounts
of polygenic signals with significant predictive power and potentially useful biological clues …

Metabolic processes can influence disease risk and provide therapeutic targets. By
conducting genome-wide association studies of 1,091 blood metabolites and 309 metabolite …

Gene–environment correlations affect associations between genetic variants and complex
traits in genome-wide association studies (GWASs). Here we showed in up to 43,516 British …

Our understanding of the genetics of the human cerebral cortex is limited both in terms of the
diversity and the anatomical granularity of brain structural phenotypes. Here we conducted a …

The use of spoken and written language is a fundamental human capacity. Individual
differences in reading-and language-related skills are influenced by genetic variation, with …

Recent years have seen the birth of sociogenomics via the infusion of molecular genetic
data. We chronicle the history of genetics, focusing particularly on post-2005 genome-wide …

Individual differences in human intelligence, as assessed using cognitive test scores, have a
well-replicated, hierarchical phenotypic covariance structure. They are substantially stable …

Research linking genetic differences with human social and behavioural phenotypes has
long been controversial. Frequently, debates about the ethical, social and legal implications …

It has been known since 1904 that, in humans, diverse cognitive traits are positively
intercorrelated. This forms the basis for the general factor of intelligence (g). Here, we …