Wound management in diabetic patient is of an extreme clinical and social concern. The
delayed and impaired healing makes it more critical for research focus. The research on …

The bubbling community of microorganisms, consisting of diverse colonies encased in a self-
produced protective matrix and playing an essential role in the persistence of infection and …

Toll-like receptors (TLRs) are a class of proteins that recognize pathogen-associated
molecular patterns (PAMPs) and damaged-associated molecular patterns (DAMPs), and …

A growing body of evidence suggests that the interaction between immune and metabolic
responses is essential for maintaining tissue and organ homeostasis. These interacting …

Background Poor wound healing is a significant complication of diabetes, which is
commonly caused by neuropathy, trauma, deformities, plantar hypertension and peripheral …

Wound healing is a major secondary complication in type 2 diabetes, which results in
significant disability and mortality, imposing a significant clinical and social burden …

Soon after epidermal growth factor (EGF) discovery, some in vivo models appeared
demonstrating its property to enhance cutaneous wound healing. EGF was the first growth …

Diabetic chronic wounds cause massive levels of patient suffering and economic problems
worldwide. The state of chronic inflammation arises in response to a complex combination of …

Abstract Diabetic Foot Ulcers (DFUs) are major complications associated with diabetes and
often correlate with peripheral neuropathy, trauma and peripheral vascular disease. It is …

Macrophages are critical for the initiation and resolution of the inflammatory phase of wound
repair. In diabetes, macrophages display a prolonged inflammatory phenotype in late wound …