Immunoregulatory effect of mast cells influenced by microbes in neurodegenerative diseases

F Girolamo, C Coppola, D Ribatti - Brain, behavior, and immunity, 2017 - Elsevier
When related to central nervous system (CNS) health and disease, brain mast cells (MCs)
can be a source of either beneficial or deleterious signals acting on neural cells. We review …

Use and future prospects of in vivo microdialysis for epilepsy studies

AG Zestos, H Luna-Munguia, WC Stacey… - ACS chemical …, 2018 - ACS Publications
Epilepsy is a common neurological disease characterized by recurrent unpredictable
seizures. For the last 30 years, microdialysis sampling has been used to measure changes …

Mast cell activation mediates blood–brain barrier impairment and cognitive dysfunction in septic mice in a histamine-dependent pathway

J Yue, Y Tan, R Huan, J Guo, S Yang, M Deng… - Frontiers in …, 2023 - frontiersin.org
Introduction Sepsis-associated encephalopathy (SAE) is a diffuse cerebral dysfunction
resulting from a systemic inflammatory response to infection; however, its pathophysiology …

Acute traumatic brain injury-induced neuroinflammatory response and neurovascular disorders in the brain

D Kempuraj, ME Ahmed, GP Selvakumar… - Neurotoxicity …, 2021 - Springer
Acute traumatic brain injury (TBI) leads to neuroinflammation, neurodegeneration, cognitive
decline, psychological disorders, increased blood-brain barrier (BBB) permeability, and …

Combined effect of trifluoperazine and sodium cromoglycate on reducing acute edema and limiting lasting functional impairments after spinal cord injury in rats

M Seblani, C Ertlen, T Coyle, P Decherchi… - Experimental …, 2024 - Elsevier
Edema formation is one of the very first events to occur after spinal cord injury (SCI) leading
to an increase of the intrathecal pressure and consequently to serious spinal tissue and …

Mast cell activation ameliorates pentylenetetrazole‐induced seizures in rats: The potential role for serotonin

E Kilinc, İE Torun, A Çetinkaya… - European Journal of …, 2022 - Wiley Online Library
Neuroinflammation plays a key role in the pathogenesis of epilepsy, but the underlying
mechanisms are not well understood. Mast cells are multifunctional immune cells that are …

Chemical biomarkers of epileptogenesis and ictogenesis in experimental epilepsy

H Luna-Munguia, AG Zestos, SV Gliske… - Neurobiology of …, 2019 - Elsevier
Epilepsy produces chronic chemical changes induced by altered cellular structures, and
acute ones produced by conditions leading into individual seizures. Here, we aim to quantify …

New anticonvulsant candidates prevent P-glycoprotein (P-gp) overexpression in a pharmacoresistant seizure model in mice

AV Enrique, ME Di Ianni, S Goicoechea… - Epilepsy & Behavior, 2021 - Elsevier
Despite the approval of a considerable number of last generation antiepileptic drugs
(AEDs)(only in the last decade, six drugs have gained Food and Drug Administration …

Abnormal innate and learned behavior induced by neuron–microglia miscommunication is related to CA3 reconfiguration

FA Méndez‐Salcido, MI Torres‐Flores, B Ordaz… - Glia, 2022 - Wiley Online Library
Neuron–microglia communication through the Cx3cr1–Cx3cl1 axis is essential for the
development and refinement of neural circuits, which determine their function into …

Food-induced acute pancreatitis

M Manohar, AK Verma… - Digestive diseases and …, 2017 - Springer
Food allergy, a commonly increasing problem worldwide, defined as an adverse immune
response to food. A variety of immune-related effector cells such as mast cells, eosinophils …